Lee County, FL Commercial Real Estate for Lease and Sale
Explore 770 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
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1133 SW Pine Island Rd, Mariner, Cape Coral, FL -
8009 Sweetwater Ranch Blvd, Coconut Point, Estero, FLProperty Type- VacantLand
For Sale- Subject To Offer
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27971 Oakland Dr, Bonita Springs, FLSpace Type- Land
For Lease- $15,000.00/MO
1 space available / 84,942 SF -
3625 Ironbridge Blvd, Winkler, Fort Myers, FLProperty Type- Industrial
For Sale- $4,695,000
Built in 2026 / Property size 12,000 SF -

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17550 East St, Fort Myers, FLSpace Type- Industrial
For Lease- $13.50/SF/YR
1 space available / 30,000 SF -
3404 Hancock Bridge Pkwy, N Fort Myers, FLProperty Type- VacantLand
For Sale- $950,000
Built in 2009 / Property size 19,471 SF -
8031 Summerlin Center Dr, Estero Bay Park, Fort Myers, FLProperty Type
- Restaurant
For Sale- $1,290,000
Built in 1997 / Property size 3,344 SF -
805 NE 8th St, Diplomat, Cape Coral, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 3,450 SF -
12960 Commerce Lakes Drive, Gateway, Fort Myers, FLProperty Type- Industrial
For Sale- $600,000
Property size 2,064 SF -
Summerlin Road At Sarahbell Ct. - Access Undetermined, Estero Bay Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,500,000
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I-75 & Bonita Beach Road, Bonita Springs, FL -
9001 Park Royal Drive, Estero Bay Park, Fort Myers, FLProperty Type- Retail
For Sale- $2,700,000
Property size 5,398 SF -
4857 Palm Beach Blvd., Buckingham, Fort Myers, FLSpace Type- Office
For Lease- $26.15/SF/YR
1 space available / 1,500 SF -
1130 North Tamiami Trail, North Fort Myers, FLProperty Type- Unassigned
For Sale- $950,000
Built in 1976 / Property size 3,460 SF -
16751 Old Us 41, Estero Bay Park, Fort Myers, FL -
8870 De Lasalle Academy Way, Olde Hickory, Fort Myers, FLProperty Type- VacantLand
For Sale- $4,500,000
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1620 Medical Lane, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $15.00/SF/YR
5 spaces available / 758 - 7,671 SF -
6202 Presidential Ct Ste A, Whiskey Creek, Fort Myers, FLProperty Type- Office
For Sale- $389,500
Built in 1983 / Property size 2,050 SF -
1130 North Tamiami Trail, North Fort Myers, FLSpace Type- Retail
For Lease- $28.00/SF/YR
1 space available / 3,460 SF -
1600 - 1628 Periwinkle Way, Sanibel, FL -
10201 Arcos Ave, Plaza del Sol, Estero, FLSpace Type- Office
For Lease- $22.00/SF/YR
3 spaces available / 1,721 - 5,734 SF -
1450-1490 East Pointe Dr, Lehigh Acres, FLProperty Type- VacantLand
For Sale- $2,995,000
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3593 Veronica S Shoemaker Blvd, Dunbar, Fort Myers, FLProperty Type- Industrial
For Sale- $1,850,000
Built in 1979 / Property size 5,760 SF -
13050 N Cleveland Ave, North Fort Myers, FL -
2507 Cleveland Ave + 2056 Franklin St, Dunbar, Fort Myers, FL -
5596 Flamingo Drive, St. James City, Saint James City, FLProperty Type- VacantLand
For Sale- $1,500,000
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16751 SR 31, Fort Myers, FL -
5811 Corporation Cir, Buckingham, Fort Myers, FL -
2200 Broadway, Dunbar, Fort Myers, FLSpace Type- Office
For Lease- $25.00 - $30.00/SF/YR
6 spaces available / 272 - 8,067 SF -
16101 Three Oaks Parkway, Fiddlesticks, Fort Myers, FLProperty Type- VacantLand
For Sale- $4,705,000
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1016 Cape Coral Parkway East, Caloosahatchee, Cape Coral, FL -
14600 Palm Beach Blvd, Olga, Fort Myers, FL -
15291 McGregor Blvd, Iona, Fort Myers, FL -
8646-8660 Gladiolus Drive, Cypress Lake, Fort Myers, FL -
6130 Idlewild St, Omni - Heritage Palms, Fort Myers, FLSpace Type- Industrial
For Lease- $16.50/SF/YR
1 space available / 8,993 SF -
14840 Sauer Park Rd, Estero Bay Park, Fort Myers, FL -
2585 FOURTH ST, Dunbar, Fort Myers, FLSpace Type- Industrial
For Lease- $15.50/SF/YR
1 space available / 8,000 SF -
9995 Estero Oaks Dr, Three Oaks, Fort Myers, FL -
16940 Gator Rd, Fiddlesticks, Fort Myers, FLSpace Type- Land
For Lease- $17,000.00/MO
1 space available / 174,240 SF -
10581 Ben C Pratt/Six Mile Cypress Parkway, Omni - Heritage Palms, Fort Myers, FLProperty Type- Industrial
For Sale- $1,399,000
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13160, 13170, 13180 & 13192 N Cleveland Avenue, North Fort Myers, FLProperty Type- Office
For Sale- $7,000,000
Built in 1986 / Property size 35,932 SF -
2717 Santa Barbara Blvd, Caloosahatchee, Cape Coral, FL -
929 Country Club Blvd, Hancock, Cape Coral, FLProperty Type
- Land
For Sale- $579,000
Property size 17,511 SF -
9820/9860 Orange River Blvd, Buckingham, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,658,000
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3201 Del Prado Boulevard South, Caloosahatchee, Cape Coral, FL -
1634 SE 47th St, Caloosahatchee, Cape Coral, FLSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 750 SF -
2312 Bruner Lane, Villas, Fort Myers, FLSpace Type- Industrial
For Lease- $12.00/SF/YR
2 spaces available / 4,400 - 17,600 SF -
1518 SE 46th Ln, Caloosahatchee, Cape Coral, FLProperty Type- Office
For Sale- $895,000
Built in 1974 / Property size 3,600 SF -
2080 McGregor Boulevard #200, Sunset - Edison, Fort Myers, FLSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 1,397 SF -
16121 Lee Rd, Fiddlesticks, Fort Myers, FLProperty Type- Office
For Sale- $650,000
Built in 2008 / Property size 2,500 SF -
16984-16998 McGregor Blvd., Iona, Fort Myers, FLProperty Type- VacantLand
For Sale- $3,250,000
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17221 Alico Center Rd, San Carlos Park, Fort Myers, FLSpace Type- Industrial
For Lease- $7,500.00/MO
1 space available / 3,000 SF