Lee County, FL Commercial Real Estate for Lease and Sale
Explore 730 listing(s) of commercial real estate in Lee County, FL to find the best space for your business.
-
2300 Mcgregor Blvd, Sunset - Edison, Fort Myers, FLSpace Type- Office
For Lease- $1,055.08 - $2,660.00/MO
6 spaces available / 283 - 828 SF -
50 Mildred Dr, Palm Lee, Fort Myers, FLSpace Type- Office
For Lease- $2,500.00/MO
1 space available / 2,500 SF -
27971 Oakland Dr, Bonita Springs, FLSpace Type- Land
For Lease- $15,000.00/MO
1 space available / 84,942 SF -
546 Pine Island Rd, Palmona Park, North Fort Myers, FL -

-
15991 N Cleveland Ave, North Fort Myers, FL -
8782/8784 Alico Rd, San Carlos Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,500,000
Built in 1982 / Property size 5,761 SF -
3622 Chiquita Blvd S, Pelican, Cape Coral, FLProperty Type- VacantLand
For Sale- $668,034
-
1751 NE Pine Island Road, Diplomat, Cape Coral, FL -
16731 McGregor Boulevard, Iona, Fort Myers, FL -
6150 Diamond Centre Court #1101, Villas, Fort Myers, FLSpace Type- Office
For Lease- $16.11/SF/YR
1 space available / 2,240 SF -
12855 Banyan Creek Drive #109-110, Iona, Fort Myers, FLProperty Type- Office
For Sale- $479,900
Built in 2003 / Property size 2,694 SF -
16950 Indy Drive, Fiddlesticks, Fort Myers, FL -
11600 Adelmo Lane, Villas, Fort Myers, FLSpace Type- Office, Industrial
For Lease- $12.50 - $27.27/SF/YR
2 spaces available / 1,100 - 30,000 SF -
1120, 1122, 1130 & 1138 Main St, San Carlos Island, Fort Myers Beach, FLProperty Type- VacantLand
For Sale- $6,900,000
Built in 1963 / Property size 4,038 SF -
10980 Enterprise Ave, Bonita Springs, FLProperty Type- Industrial
For Sale- $4,500,000/SF
Built in 1974 / Property size 20,000 SF -
16501 Michael G Rippe Parkway, Fiddlesticks, Fort Myers, FLProperty Type- VacantLand
For Sale- $6,590,000
-
15865 Brothers Ct, Estero Bay Park, Fort Myers, FLSpace Type- Industrial
For Lease- $12.75/SF/YR
1 space available / 12,800 SF -
1750 N Tamiami Trl, North Fort Myers, FL -
7200 Bayshore Rd, North Fort Myers, FLProperty Type- Other
For Sale- $8,100,000
-
22770 S Tamiami Trl, Fountain Lakes, Estero, FLProperty Type- Land
For Sale- $2,150,000
-
16225/16235 Pine Ridge Rd, Estero Bay Park, Fort Myers, FLProperty Type- Industrial
For Sale- $19,195,000
Built in 2026 / Property size 76,780 SF -
13770 Jetport Commerce Pkwy, Southwest Florida Airport, Fort Myers, FLSpace Type- Industrial
For Lease- $17.00 - $19.00/SF/YR
4 spaces available / 1,936 - 2,082 SF -
2004 Rosa Ct, Lehigh Acres, FLProperty Type- Office
For Sale- $340,000
Property size 1,304 SF -
3324 Stringfellow Rd, St. James City, Saint James City, FLProperty Type- Retail
For Sale- Call for Price
Built in 1959 / Property size 4,389 SF -
4820 Orange Grove Blvd, North Fort Myers, FLProperty Type- Other
For Sale- $1,450,000
Property size 6.95 Acre -
16960 Alico Mission Way, Estero Bay Park, Fort Myers, FL -
16940 Gator Rd, Fiddlesticks, Fort Myers, FLSpace Type- Land
For Lease- $17,000.00/MO
1 space available / 152,460 SF -
2189 N Tamiami Trail, Palmona Park, North Fort Myers, FLProperty Type- VacantLand
For Sale- Call For Details
-
1693 Baseline Ct , Poinsettia Park, Fort Myers, FLSpace Type- Land
For Lease- $20,000.00/SF/MO
1 space available / 144,183 SF -
4401 Skates Circle, Buckingham, Fort Myers, FLProperty Type- Land
For Sale- $1,390,880
Property size 19.87 Acre -
122 Chiquita Boulevard South, Mariner, Cape Coral, FLSpace Type
- Office
For Lease- $35.00 - $40.00/SF/YR
2 spaces available / 1,014 SF -
9490 Corkscrew Rd, Estero Town Center, Estero, FLProperty Type- VacantLand
For Sale- $1,971,000
Built in 2000 / Property size 2,491 SF -
7205 Estero Boulevard, Fort Myers Beach, FLSpace Type- Retail
For Lease- $45.00/SF/YR
1 space available / 2,225 SF -
2534 Santa Barbara Boulevard South, Hancock, Cape Coral, FL -
8009 Sweetwater Ranch Blvd, Coconut Point, Estero, FLProperty Type- VacantLand
For Sale- Subject To Offer
-
1450-1490 East Pointe Dr, Lehigh Acres, FLProperty Type- VacantLand
For Sale- $2,995,000
-
1111/1121/1133 Ceitus Terrace, Mariner, Cape Coral, FL -
16956 McGregor Blvd, Iona, Fort Myers, FLProperty Type- Office
For Sale- $495,000
Built in 1985 / Property size 4,023 SF -
9820/9860 Orange River Blvd, Buckingham, Fort Myers, FLProperty Type- Other
For Sale- $1,950,000
Property size 10.33 Acre -
2707 NW 26th St, Burnt Store, Cape Coral, FLProperty Type- VacantLand
For Sale- $100,000
-
25270 Bernwood Dr, Bonita Springs, FLSpace Type
- Industrial
For Lease- $14.00 - $17.00/SF/YR
3 spaces available / 1,873 - 2,521 SF -
10580 Colonial Boulevard, Colonial Country Club, Fort Myers, FL -
10581 Ben C Pratt/Six Mile Cypress Parkway, Omni - Heritage Palms, Fort Myers, FLProperty Type- Industrial
For Sale- $1,399,000
-
9901 Gladiolus Drive, Estero Bay Park, Fort Myers, FLProperty Type- VacantLand
For Sale- $6,100,000
-
3155 Fowler St, Winkler, Fort Myers, FLProperty Type- VacantLand
For Sale- $849,000
-
12575 S Cleveland Ave, Villas, Fort Myers, FLSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 2,817 SF -
27180 Bay Landing Drive, Bonita Springs, FLSpace Type- Office
For Lease- $17.00 - $20.00/SF/YR
3 spaces available / 2,170 - 3,661 SF -
8646-8660 Gladiolus Drive, Cypress Lake, Fort Myers, FL -
9490-9500 Corkscrew Rd, Plaza del Sol, Estero, FLProperty Type- Other
For Sale- $1,971,000
Property size 95,263 SF -
1314-1322 Lafayette St, Caloosahatchee, Cape Coral, FL
-
2200 Broadway, Dunbar, Fort Myers, FLSpace Type- Office
For Lease- $25.00 - $30.00/SF/YR
6 spaces available / 272 - 8,067 SF -
2270 Cleveland Ave, Sunset - Edison, Fort Myers, FLProperty Type- VacantLand
For Sale- $1,900,000
-
13361 Saddle Rd, Southwest Florida Airport, Fort Myers, FLSpace Type- Industrial
For Lease- $13.00/SF/YR
1 space available / 4,876 SF