Madison County, IL Commercial Real Estate for Lease and Sale
Explore 329 listing(s) of commercial real estate in Madison County, IL to find the best space for your business.
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100 N Main St, Edwardsville, ILSpace Type- Office
For Lease- $25.00/SF/YR
1 space available / 1,000 SF -
140 Wilma Dr, Maryville, IL -
NW Quadrant of I-64 and IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $246,440.7
Property size 0.73 Acre -
Wesley Drive, Wood River, IL -

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1435 Vaughn Road, Wood River, IL -
4235 S State Route 159, Glen Carbon, ILSpace Type- Retail
For Lease- $17.00/SF/YR
1 space available / 1,000 SF -
300 Harmony Lane, Edwardsville, ILProperty Type- VacantLand
For Sale- $65,000/Acre
Property size 6 Acre -
7700 Plummer Business Dr, Troy, ILProperty Type- VacantLand
For Sale- $132,531
Built in 2000 / Property size 0.87 Acre -
Wesley and Rock Hill Rd, Wood River, ILProperty Type- VacantLand
For Sale- $50,000/Acre
Property size 35 Acre -
8003-8016 Builders Ct., Edwardsville, ILProperty Type- VacantLand
For Sale- $125,000/Acre
Property size 2 Acre -
NW Quadrant Of I-64 And IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $370,260
Property size 0.85 Acre -
4215 S State Route 159th, Glen Carbon, ILSpace Type- Office
For Lease- $17.00/SF/YR
1 space available / 1,000 SF -
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Gateway Commerce Center Drive, Edwardsville, ILProperty Type- VacantLand
For Sale- $1,850,000
Property size 21 Acre -
Edwardsville Club Plaza, Edwardsville, ILProperty Type- VacantLand
For Sale- $150,000
Property size 0.38 Acre -
305 E Main St, Collinsville, ILProperty Type- VacantLand
For Sale- $110,000
Property size 0.4 Acre -
NW Quadrant of I-64 and IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $327,462.3
Property size 0.97 Acre -
1705 Homer Adams Parkway, Alton, IL -
4700 South State Street 159, Glen Carbon, ILProperty Type- VacantLand
For Sale- $350,000
Property size 2.2 Acre -
3227 West Chain of Rocks Road, Granite City, ILSpace Type- Retail
For Lease- $12.00/SF/YR
1 space available / 2,318 SF -
3675 Nameoki Road, Granite City, ILSpace Type- Retail
For Lease- $7.68 - $17.00/SF/YR
4 spaces available / 1,200 - 14,500 SF -
140 Wilma Dr, Maryville, ILProperty Type- VacantLand
For Sale- $72,000/Acre
Property size 146 Acre -
122-208 E Chain of Rocks Rd, Mitchell, Granite City, IL -
5 Commercial Court, Highland, IL -
241 N Main St, Edwardsville, ILSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 4,624 SF -
4212 S State Route 159, Glen Carbon, ILProperty Type- VacantLand
For Sale- $525,000
Property size 0.45 Acre -
140 Wilma Dr, Maryville, IL -
7701 Plummer Business Dr, Troy, ILProperty Type- VacantLand
For Sale- $126,992
Property size 0.73 Acre -
7308 Godfrey Road, Godfrey, ILProperty Type- VacantLand
For Sale- $27,955/Acre
Property size 8 Acre -
1830 Vandalia St, Collinsville, ILProperty Type- VacantLand
For Sale- $149,000
Property size 1.29 Acre -
900 Tonsor Rd, Alton, ILProperty Type- Industrial
For Sale- $675,000
Property size 15,000 SF -
5171 Pagano Crt, Pontoon Beach, ILProperty Type- VacantLand
For Sale- $548,856
Property size 1.05 Acre -
1511 Niedringhaus Ave, Granite City, IL -
2805 E 23rd St, Granite City, ILProperty Type- Other
For Sale- $165,000
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400 Landmarks Blvd, Alton, ILSpace Type- Retail
For Lease- $25.00/SF/YR
2 spaces available / 1,865 - 2,415 SF -
7346 State Route 162, Troy, ILProperty Type- Office
For Sale- $1,150,000
Built in 2022 / Property size 6,000 SF -
401 Janet Beth Way, Highland, IL -
Gateway Commerce Center Dr E and Inner Park Dr, Edwardsville, ILProperty Type- VacantLand
For Sale- $225,000/Acre
Property size 4.73 Acre -
NW Quadrant of I-64 and IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $335,412
Property size 0.77 Acre -
4501 State Route 159, Glen Carbon, ILProperty Type- VacantLand
For Sale- $500,000
Property size 0.66 Acre -
5 Commercial Court, Highland, IL -
2600 Homer Adams Parkway, Alton, IL -
5 Commercial Court, Highland, IL -
900 St Thomas Rd, Granite City, ILSpace Type- Land
For Lease- $1,850.00/Acre/MO
1 space available / 87,120 SF -
111 N 2nd St, Edwardsville, ILSpace Type- Office
For Lease- $24.00/SF/YR
1 space available / 1,658 SF -
1328-1336 Mercantile Dr, Highland, ILSpace Type- Office
For Lease- $10.00/SF/YR
1 space available / 3,040 SF -
5715 Inner Park Drive, Edwardsville, IL -
NW Quadrant Of I-64 And IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $300,455.1
Property size 0.89 Acre -
5998 Redbud Ln, Edwardsville, ILSpace Type- Industrial
For Lease- $12.00/SF/YR
1 space available / 3,600 SF -
140 Wilma Dr, Maryville, IL -
1511 Niedringhaus Ave, Granite City, IL -
2600 Homer Adams Parkway, Alton, IL -
NW Quadrant Of I-64 And IL-157, Caseyville, ILProperty Type- VacantLand
For Sale- $361,548
Property size 0.83 Acre