Please provide a location to search for

Saint Louis, MO Commercial Real Estate

4,034 Commercial Properties Available in Saint Louis, MO

Showing top 200 results

St. Louis, MO Economic Overview

Location Photo

Located on the banks of the mighty Mississippi river, St. Louis is one of the oldest and most well-established ports, trading posts, and business centers of the United States. St. Louis’ location on major transportation routes almost right in the middle of the country has helped create an environment of almost continual economic growth, which still thrives today. With a population of only 311,404 in St, Louis proper, and over 2 million in the metropolitan and Greater St. Louis areas, the region offers an established economic environment, in which businesses, both new and old, can thrive.

St. Louis’ economic output, according to a 2015 report, was just over $155 billion dollars, ranking them at 21st-highest GDP in the country. These numbers are fueled largely by major corporations that call St. Louis home, such as Anheuser-Busch, Express Scripts, Monsanto, Edward Jones Investments, and a number of other corporate regional headquarters. On top of this, St. Louis is home to a number of health care and biotechnology companies that contribute to economic growth, including Boeing and Pfizer. Also involved in St. Louis’s economy are major hospital and research centers, most notably Washington University in St. Louis and Saint Louis University.

St. Louis, MO Commercial Real Estate Market

The St. Louis commercial market has expanded in 2016, due largely to major corporations moving into town, such as two Amazon corporate leases and a Schnucks Markets distribution center. Construction on new sites has intensified and will continue to do so, throughout 2017. With demand going up, rental rates on already-constructed properties will continue to rise, albeit at a slower rate than other cities. This slower rate is due largely to the fact that St. Louis regional government and private businesses have funded numerous developmental and construction projects in the area, resulting in close to 3 million square feet of new commercial real estate space.

The Downtown St. Louis office market includes numerous corporate headquarters, business offices, and retail spaces. The area is the home of numerous corporate headquarters, most notably Hardee’s, Stifel Nicolaus, and Laclede Group. Downtown is also home to two major professional sports teams: the Blues (hockey) and Cardinals (baseball), each surrounded by numerous retail and office properties.

The University City and Delmar Loop commercial real estate market includes numerous businesses and real estate available for entertainment, culture, retail and dining. Located close to the border between St. Louis and University City, Missouri, the Delmar Loop has been expanding into neighboring areas over the past few years. Due to its cultural and entertainment attractions, Delmar Loop is bound to continue expanding, affording opportunity for businesses looking to establish themselves in the area.

The Metro East office space market is one of the areas of St. Louis that has been expanding in recent years. Across the river in Illinois, but still part of the St. Louis metropolitan area, Metro East’s latest addition is an Amazon factory. Numerous lots for industrial spaces have been put on the market, with further development plans in the works.

St. Louis, Office Sales Volume

Data provided by Yardi Matrix, for properties larger than 50K SF, which sold at over $5M.

St. Louis, Office Transactions

Data provided by Yardi Matrix, for properties larger than 50K SF, which sold at over $5M.

Saint Louis, MO Commercial Inventory Breakdown

Office Spaces

Total: 44,612,155 SF

Data provided by Yardi Matrix, properties over 50k SF, includes office with retail

By square footage range:

  • 50k to 100k SF: 8,271,053 SF / 18.54% of total office
  • 100k to 500k SF: 24,330,829 SF / 54.54% of total office
  • 500k to 1M SF: 6,114,141 SF / 13.71% of total office
  • > 1M SF: 5,896,132 SF / 13.22% of total office

By class:

  • Class A: 23,570,173 SF / 52.83% of total office
  • Class B: 16,811,797 SF / 37.68% of total office
  • Class C: 326,107 SF / 0.73% of total office


Total: 58,000 SF

Data provided by Yardi Matrix, properties over 50k SF

By square footage range:

  • 50k to 100k SF: 58,000 SF / 100% of total industrial

Employment in St. Louis, MO


St. Louis’ economy is driven largely by the corporate headquarters in the region, even though the biggest employers are not always corporations. In the latest reports on employment, BJC Health Care, a non-profit health care provider associated with the Barnes-Jewish Hospital and St. Louis Children’s Hospital, which are both affiliated in turn with the Washington University School of Medicine, employed over 24,000 people. SSM Health, a Catholic health care system, employed another 13,000 people in the St. Louis region.

For corporate employment numbers, the two largest are Wal-Mart and Boeing Defense, Space and Security. Wal-Mart employs close to 22,000 people in the St. Louis area, while Boeing employs 15,000 people.

Washington University in St. Louis, a feeder of talent to all of those companies, rounds out the list, with 14,451 employees.

Education in St. Louis, MO

St. Louis is served by the St. Louis Public School system, which runs over 75 schools, with 25,000 students in the system. There are also private schools in the city, the most notable being the Catholic schools operated by the Archdiocese of St. Louis, which runs over 100 elementary schools and high schools.

St. Louis is often noted for its world-class universities. The most notable of these institutions is the Washington University of St. Louis, which operates a medical school that has been consistently ranked in the top ten in the nation and a tier-1 law school. St. Louis University, a private Catholic university, is also ranked highly and is known world-wide for its research.

Commuting Time in St. Louis, MO

St. Louis is highly accessible by road, rail, and air transportation, along with boating transportation on the Mississippi. Four interstate highways run through the area, many of which cross downtown itself. Due to St Louis’ Central Corridor being a bit more spread out than other cities, the downtown traffic can be lighter than other cities, but still busy during rush hours.

St. Louis is served by MetroLink light rail, which connects most neighborhoods in St. Louis. This cuts down on some of the road traffic.

Saint Louis Demographics


  • Total Population926,121
  • Male Population(47.6 %) 440,572
  • Female Population(52.4 %) 485,548
  • Median Age36.40


  • Average Household Income$83,030
  • Median Household Income$40,685
  • Median Income Under 25$24,457
  • Median Income 25-44$51,960
  • Median Income 45-64$48,646
  • Median Income Over 65$33,965


Amazon’s search for a new home has stirred up city officials and developers across the country, and 238 applicants across North America have expressed interest in housing the company’s next headquarters. Of course, the retail giant has a few requirements: the chosen metropolitan area should idea...

  As developers fight over the increasingly limited amount of undeveloped land in major U.S. urban centers, they are forced to look elsewhere for solutions. Enter the concept of adaptive reuse—the restoration or redevelopment of a building for a different use than its original purpose. Cities li...

The key to capitalizing on today’s ever-growing apartment rental market? It’s simple: build more units. According to the National Multifamily Housing Council, demand for rental units is so high in the U.S. that we would need a whopping 4.6 million new units by 2030 just to keep up. Couple that d...

CommercialCafé is your first and only stop when it comes to commercial real estate leasings in Saint Louis, MO. Search through our extensive selection of commercial properties for lease with current space availability in the area ranging between 963 square feet and 963 square feet. Discover the right property from our 4034 listings by using our advanced search function, which includes search by property type, space availability, management company, lease rates, and more.