Saint Louis, MO Commercial Real Estate for Lease and Sale

Explore 318 listings of Saint Louis commercial real estate to find the best space for your business.

S. Grand Mixed Use Building w/ Turnkey Restaurant

3159 S Grand Blvd, Tower Grove South, Saint Louis, MO
Property

Mixed Use

7,208 SF
Year Built

1909
For Sale

$795,000
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CIC St. Louis
CIC
4220 Duncan Avenue, St. Louis, MO
Services

Open Workspace

Private Office
Amenities

Bike storage

Complimentary coffee & tea

Game room

High-speed wifi

Lab space

Parking

Podcast room

Printer

Projector

Receptionist/Secretarial services
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Turnkey Hair Salon

5839 Hampton Avenue, St. Louis Hills, St. Louis, MO
Property

Retail

900 SF
Availability

1 Space

900 SF
For Lease

$30.00/SF/YR
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245 Union Blvd

245 Union Blvd, DeBaliviere Place, Saint Louis, MO
Property

Unassigned

165,661 SF
Availability

1 Space

8,263 SF
Year Built

1918
For Lease Contact for pricing
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Office Coworking Retail Industrial

Office Retail Industrial Land
Cupples One Office Building

1000 Clark Avenue, Downtown Saint Louis, St. Louis, MO
Property

Office

104,666 SF
Availability

4 Spaces

27,155 SF
Year Built

1900
For Lease

$19.50/SF/YR
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4330 S Broadway (29,000sf Warehouse/Retail)

4330 S Broadway, Mount Pleasant, Saint Louis, MO
Property

Industrial

29,390 SF
Year Built

1968
For Sale

$1,790,000/SF
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Carondelet Retail/Flex Building for Sale

6022 Virginia Avenue, Carondelet, St. Louis, MO
Property

Retail

3,000 SF
Year Built

1951
For Sale

$315,000
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Cinderella Building

2731-41 Cherokee St, Benton Park West, Saint Louis, MO
Property

Mixed Use

24,927 SF
Availability

1 Space

800 SF
Year Built

1913
For Lease

$15.00/SF/YR
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620 Shenandoah & 2322 South 7th Street

620 Shenandoah & 2322 South 7th Street, Kosciusko, Saint Louis, MO
Property

Industrial

37,545 SF
For Sale

$1,895,000
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3548-3550 Magnolia Ave

3548-3550 Magnolia Ave, Tower Grove East, Saint Louis, MO
Property

Multi-Family

5,481 SF
Year Built

1904
For Sale

$499,000
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Tower Grove South - Adaptive Reuse Opportunity

4101-4125 Humphrey Street, Tower Grove South, St. Louis, MO
Property

Special Purpose

16,988 SF
Year Built

1925
For Sale

$1,999,000
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5730 Wise Ave

5730 Wise Ave, Cheltenham, Saint Louis, MO
Property

Industrial

7,558 SF
Year Built

1947
For Sale

$895,000
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600 Washington

600 Washington Ave., Downtown Saint Louis, St. Louis, MO
Property

Office

385,000 SF
Availability

12 Spaces

181,431 SF
Year Built

1986
For Lease

$18.75/SF/YR
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3140 Park Avenue

3140 Park Avenue, The Gate District, Saint Louis, MO
Property

Industrial

35,000 SF
For Sale

$2,000,000
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Tower Grove South Free Standing Retail

3765 Gravois Avenue, Tower Grove South, St. Louis, MO
Property

Retail

2,496 SF
For Sale

$599,000
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2233 Delmar Blvd

2219-2233 Delmar Blvd, Downtown West Saint Louis, Saint Louis, MO
Property

Industrial

92,000 SF
For Sale Contact Broker
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Grant School Apartments

3009 Pennsylvania Ave, Tower Grove East, Saint Louis, MO
Property

Multi-Family

27,300 SF
Year Built

1905
For Sale

$2,600,000
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Dutchtown South Portfolio

3857 Gustine Avenue, Dutchtown, St. Louis, MO
Property

Multi-Family

13,600 SF
Year Built

1929
For Sale

$1,200,000
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5000 Manchester Ave

5000 Manchester Avenue, The Hill, St. Louis, MO
Property

Office

20,808 SF
Availability Contact for availability
Year Built

1971
For Lease Contact for pricing
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501-519 North Grand Blvd

501 North Grand Blvd, Covenant Blu - Grand Center, St. Louis, MO
Property

Office

49,754 SF
Availability

2 Spaces

9,535 SF
Year Built

1940
For Lease

$22.00/SF/YR
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111 Winnebago St

111 Winnebago St , Benton Park West, St Louis, MO
Property

Industrial

340,000 SF
Availability

2 Spaces

75,000 SF
Year Built

1954
For Lease

$6.50/SF/YR
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Turn-Key Brewery and Restaurant

721-723 N. 2nd St, Downtown Saint Louis, St. Louis, MO
Property

Retail

15,552 SF
Availability

3 Spaces

7,800 SF
Year Built

1896
For Lease Contact for pricing
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2345 Pine Street

2345 Pine Street, Downtown West Saint Louis, Saint Louis, MO
Property

Office

2,500 SF
Year Built

1961
For Sale Contact Broker
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900 Hodiamont Avenue

900 Hodiamont Ave, West End Saint Louis, Saint Louis, MO
Property

Industrial

48,000 SF
Availability

1 Space

24,000 SF
Year Built

1926
For Lease

$6.50/SF/YR
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Cortex 1 - Office/Lab Space For Lease

4320 Forest Park Ave, Central West End Saint Louis, St. Louis, MO
Property

Office
Availability

1 Space

27,048 SF
For Lease Contact for pricing
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3 -11 South Newstead Avenue

3 -11 South Newstead Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office

5,175 SF
Availability

4 Spaces

6,990 SF
Year Built

1905
For Lease Contact for pricing
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The Chouteau Building

4030 Chouteau Avenue, Forest Park South East, St Louis, MO
Property

Office

37,500 SF
Availability

1 Space

30,000 SF
Year Built

1921
For Lease

$12.75/SF/YR
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1700 S Jefferson Ave

1700 S Jefferson Ave, Lafayette Square, Saint Louis, MO
Property

Mixed Use

16,000 SF
Availability

1 Space

5,170 SF
Year Built

2008
For Lease

$6.00/SF/YR
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Deloitte Building

100 South 4th Street , Downtown West Saint Louis, Saint Louis, MO
Property

Office

287,250 SF
Availability

9 Spaces

162,463 SF
Year Built

1986
For Lease

$17.75/SF/YR
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5437 Page Blvd

5437 Page Blvd, Hamilton Heights, Saint Louis, MO
Property

Multi-Family

15,444 SF
Year Built

1908
For Sale

$1,400,000
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4981 Rosalie St

4981 Rosalie St, Mark Twain, Saint Louis, MO
Property

Multi-Family

11,548 SF
Year Built

1928
For Sale

$1,100,000
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Tudor Building in Downtown West

1901 Washington Ave, Downtown West Saint Louis, Saint Louis, MO
Property

Retail

23,585 SF
Availability

2 Spaces

5,510 SF
Year Built

1915
For Lease

$18.00/SF/YR
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2315 Pine Street

2315 Pine Street, Downtown West Saint Louis, Saint Louis, MO
Property

Office

8,653 SF
Availability

1 Space

7,457 SF
Year Built

1964
For Lease

$12.50/SF/YR
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Downtown West Restaurant Space

1818 Washington Ave, Downtown West Saint Louis, Saint Louis, MO
Property

Retail

18,591 SF
Availability

1 Space

3,831 SF
Year Built

1924
For Lease

$18.00/SF/YR
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Monkey Building

1430 Washington Avenue, Downtown West Saint Louis, St. Louis, MO
Property

Office

27,045 SF
Availability

4 Spaces

7,719 SF
Year Built

2006
For Lease

$10.00 - $24.00/SF/YR
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Industrial Showroom

8393 Hall Street, Baden, St. Louis, MO
Property

Industrial

12,500 SF
Year Built

1999
For Sale

$1,250,000
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Prominent Free-Standing Retail Building

5441 Hampton Avenue, St. Louis Hills, St. Louis, MO
Property

Retail

2,220 SF
Availability

1 Space

2,220 SF
Year Built

1949
For Lease

$18.00/SF/YR
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3948 Laclede Avenue

3948 Laclede Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office

35,000 SF
Availability

1 Space

35,000 SF
Year Built

1908
For Lease

$20.00/SF/YR
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The Nicholas

1500-1506 s. grand St. Louis, The Gate District, St. Louis, MO
Property

Retail

1,245 SF
Availability

1 Space

1,245 SF
For Lease

$28.00/SF/YR
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3224 South Kingshighway Blvd

3224 South Kingshighway Blvd, Tower Grove South, St. Louis, MO
Property

Retail

68,584 SF
Year Built

1920
For Sale

$1,600,000
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US Bank Plaza

505 N. Seventh St., Downtown Saint Louis, St. Louis, MO
Property

Office

641,604 SF
Availability

21 Spaces

234,961 SF
Year Built

1975
For Lease

$20.00/SF/YR
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1120 Montrose Ave

1120 Montrose Ave, The Gate District, Saint Louis, MO
Property

Industrial

71,164 SF
Availability

1 Space

30,713 SF
Year Built

1937
For Lease

$6.00/SF/YR
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620 Shenandoah Avenue

620 Shenandoah Avenue , Kosciusko, Saint Louis, MO
Property

Industrial

18,975 SF
For Sale

$1,100,000
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Downtown STL Restaurant / Bar / Event Condo

920 Olive Street, Downtown Saint Louis, St. Louis, MO
Property

Retail

12,528 SF
Availability Contact for availability

For Lease Contact for pricing
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3701 Lindell Bivd

3701 Lindell Bivd, Covenant Blu - Grand Center, St. Louis, MO
Property

Unassigned
Availability Contact for availability

For Lease Contact for pricing
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Kingshighway Development Site

3500 South Kingshighway Boulevard, Tower Grove South, St. Louis, MO
Property

Retail

11,674 SF
Year Built

1952
For Sale

$1,499,000
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1115 Hampton Ave

1115 Hampton Ave, Clayton Tamm, Saint Louis, MO
Property

Retail

4,038 SF
For Sale

$850,000
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Build-to-Suit Opportunity: Two Foundry Way

3825 Foundry Way, Midtown Saint Louis, Saint Louis, MO
Property

Office

83,000 SF
Availability

1 Space

16,600 SF
For Lease Contact for pricing
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Ludwig Building Downtown Office and Retail

1006 Olive Street, Downtown Saint Louis, St. Louis, MO
Property

Mixed Use

44,236 SF
Availability

2 Spaces

3,947 SF
Year Built

1905
For Lease

$12.50/SF/YR
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Class A Office Space Downtown

1010 Market Street, Downtown Saint Louis, St. Louis, MO
Property

Office
Availability

1 Space

71,965 SF
For Lease Contact for pricing
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Cubework St. Louis

601 East Red Bud Avenue, North Riverfront, St. Louis, MO
Property

Industrial

61,118 SF
Availability

3 Spaces

56,000 SF
Year Built

1942
For Lease Contact for pricing
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1210 Washington Ave

1210 Washington Avenue, Downtown West Saint Louis, St. Louis, MO
Property

Office

14,900 SF
Availability

1 Space

1,820 SF
Year Built

1925
For Lease

$12.00/SF/YR
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Saint Louis commercial real estate market incorporates 5,996,284 square feet of office space across 103 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Saint Louis commercial real estate market includes 2,384,781 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Saint Louis market, there is a total of 4,890,273 square feet of industrial property.

The listing inventory in Saint Louis incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Saint Louis is represented by Office space, which accounts for 2,134,925 square feet of available listings. Industrial space available in Saint Louis adds up to 2,129,336 square feet.

Meanwhile, most of the listings of commercial property for sale in Saint Louis are in the Industrial category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Saint Louis is $16.42 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Saint Louis can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset. What’s more, each commercial property type makes its own rent market: while the average rent for office space rested at $24.6 per square foot, industrial space in Saint Louis saw average rents of $5.28 per square foot.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Saint Louis, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Saint Louis is in the Downtown Saint Louis neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Downtown Saint Louis area.

Meanwhile, retail space opportunities are most abundant in the Downtown Saint Louis submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in North Riverfront.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $22.95 per square foot. In particular, the property type commanding the highest lease rates in Saint Louis was Office space.

Conversely, the highest sale price last year was $9,700,000 that is located at 8640 Evans Avenue.

The average size of a commercial property in Saint Louis depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Saint Louis, the average size of an office property is 74,954 square feet.
Retail properties here incorporate an average of 27,731 square feet.
Industrial space in Saint Louis is in buildings that are, on average 81,505 square feet in size.

Saint Louis, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Saint Louis currently add up to 5,344,860 square feet. The market offers 80 active office listing(s), which amount to 2,134,925 square feet and account for 40% of commercial spaces on the market. Local retail availability includes 749,957 square feet across 74 retail space(s). Industrial space for rent opportunities in Saint Louis amount to 2,129,336 square feet across a total of 32 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	80	2,134,925
Retail	74	749,957
Industrial	32	2,129,336
Other	10	330,642

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Saint Louis, MO. Currently, there is 2,924,662 square feet of commercial property for sale here , which includes 23 office building(s) for sale , 28 retail investment opportunity listing(s) , and 31 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	23	590,602
Retail	28	267,477
Industrial	31	1,639,429
Other	31	427,154

Saint Louis, MO Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Saint Louis, MO?

What factors affect the price of commercial real estate in Saint Louis, MO?

What is the average rent for commercial space in Saint Louis, MO?

What are the best areas for commercial real estate in Saint Louis, MO?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Saint Louis, MO?

Saint Louis, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

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