Des Peres, MO Commercial Real Estate for Lease and Sale

Explore 11 listing(s) of commercial real estate in Des Peres, MO to find the best space for your business.

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13075 Manchester Road

13075 Manchester Road, Des Peres, St. Louis, MO
Space Type

Office
For Lease

$32.50/SF/YR
1 space available / 5,630 SF
View Details
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Topping Office Center

13100 Manchester Road, Des Peres, St. Louis, MO
Space Type

Office
For Lease

$19.00/SF/YR
2 spaces available / 2,079 - 2,173 SF
View Details
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Des Peres Corners

12332 Manchester Road, Des Peres, MO
Space Type

Retail, Office
For Lease Contact for pricing

3 spaces available / 1,386 - 5,335 SF
View Details
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13421 Manchester Road

13421 Manchester Road, Des Peres, MO
Space Type

Office
For Lease Contact for pricing

1 space available / 2,000 SF
View Details
13421 Manchester Rd

13421 Manchester Rd, Des Peres, MO
Property Type

Office
For Sale

$900,000
Property size 4,000 SF
View Details
Des Peres Shopping Center

12085 Manchester Road, Des Peres, MO
Space Type

Office, Retail
For Lease Contact for pricing

17 spaces available / 101 - 1,842 SF
View Details
Olympic Oaks Village

12139 Manchester Road, Des Peres, MO
Space Type

Retail
For Lease Contact for pricing

2 spaces available / 1,400 - 3,164 SF
View Details
13205 Manchester Road

13205 Manchester Road, Des Peres, MO
Space Type

Land
For Lease Contact for pricing

1 space available / 87,120 SF
View Details
11768 Manchester Road

11768 Manchester Road, Des Peres, St. Louis, MO
Property Type

Retail
For Sale Contact for pricing

Property size 5,460 SF
View Details
11768 Manchester Road

11768 Manchester Road, Des Peres, St. Louis, MO
Space Type

Retail
For Lease Contact for pricing

1 space available / 5,460 SF
View Details
Colonnade Center

1131 Colonnade Center, Des Peres, MO
Space Type

Retail
For Lease

$28.00/SF/YR
1 space available / 3,000 SF
View Details

Frequently Asked Questions

CommercialCafe’s CRE offering in Des Peres is enabled by a network of 20 active brokers from 10 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Des Peres, MO Commercial Space Listings

Commercial Space for Lease - Breakdown

The 12 listings for commercial real estate currently available for rent in Des Peres add up to 132,541 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	6	14,443
Retail	5	30,978
Other	1	87,120

Office properties:

The market has 6 active office listings, encompassing 14,443 square feet.
Des Peres office spaces currently listed on CommercialCafe represent 50% of the total commercial real estate market in Des Peres, compared to an average of 53% across all markets tracked by CommercialCafe.

Retail Space:

There are 5 retail listings available, adding up to a total of 30,978 square feet.
Retail spaces account for approximately 41% of the local commercial market, while the average share taken up by retail in all U.S. markets is 46%.

The data presented in this section was last updated as of October 07, 2026

Commercial Space for Sale - Breakdown

There are currently 2 properties listed for sale in the Des Peres market, adding up to 9,460 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

1 office property
1 retail property

The data presented in this section was last updated as of October 07, 2026

Property Type	Count of Listings	Total Sq. Ft.
Office	1	4,000
Retail	1	5,460

Des Peres, MO Commercial Real Estate for Lease and Sale

13075 Manchester Road

Topping Office Center

Des Peres Corners

13421 Manchester Road

13421 Manchester Rd

Des Peres Shopping Center

Olympic Oaks Village

13205 Manchester Road

11768 Manchester Road

11768 Manchester Road

Colonnade Center

Frequently Asked Questions

Des Peres, MO Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

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