Durham, NC Commercial Real Estate for Lease and Sale

Explore 329 listing(s) of commercial real estate in Durham, NC to find the best space for your business.

CRE Market FAQs

Research Tri-Center North IV

2710 Weck Drive, Taylor Estates, Durham, NC
Space Type

Industrial
For Lease Contact for pricing

1 space available / 108,750 SF
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4900 Prospectus Drive

4900 Prospectus Drive, Research Triangle Park, Durham, NC
Space Type

Industrial
For Lease Contact for pricing

2 spaces available / 40,079 - 42,794 SF
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411 Andrews Rd

411 Andrews Rd, American Village, Durham, NC
Space Type

Office
For Lease

$18.00/SF/YR
1 space available / 2,080 SF
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1525 Glenn School Road

1525 Glenn School Road, Gorman, Durham, NC
Space Type

Land
For Lease Contact for pricing

3 spaces available / 46,609.2 - 56,628 SF
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5112 Neal Rd

5112 Neal Road, Bennet Place, Durham, NC
Space Type

Other
For Lease

$4,500.00/MO
1 space available / 3,000 SF
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601 S Alston Ave

601 S Alston Ave, North Carolina Central University, Durham, NC
Property Type

VacantLand
For Sale

$1,250,000
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Triangle Meeting & Studio Space - 2603 South Miami Boulevard

2603 South Miami Boulevard, Durham, NC
Space Type

Meeting Rooms
For Lease

From $25/hour
Space for 1 to 75 people
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7820 NC 751 Hwy

7820 NC 751 Hwy, Eagle's Pointe, Durham, NC
Property Type

Retail
For Sale

$2,541,000
Built in 2012 / Property size 5,000 SF
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830 N Mangum St

830 N Mangum St, Old Five Points, Durham, NC
Property Type

Office
For Sale

$695,000
Property size 3,173 SF
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University Hill

University Dr & Shannon Rd, Valley Run, Durham, NC
Space Type

Retail
For Lease Contact for pricing

3 spaces available / 1,000 - 1,363 SF
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2202 East Geer Street

2202 E Geer St, Gorman, Durham, NC
Space Type

Industrial
For Lease

$5,500.00/MO
1 space available / 40,075.2 SF
View Details

Frequently Asked Questions

Here is a rundown of the primary commercial real estate property types currently available in Durham:
- Office Space: The market includes 12,839,171 square feet of office spaces in addition to 457 coworking locations.
- Retail Space: Between malls, restaurants and stores, Durham is home to 4,565,886 square feet of available retail space.
- Industrial Space: Warehouses, distribution centers, manufacturing facilities and other industrial types total 4,710,214 square feet of available space in Durham.
The average rent for commercial real estate in Durham is $26.18 per square foot. However, specific rates may vary widely by property type, class and quality. The cheapest commercial space in Durham costs $1.65, while the city’s premium locations ask up to $70.83.
Office space here averages $33.69 per square foot while industrial space averages $14.9 per square foot. The variation reflects differences in property types, quality, and demand. 
Here is a breakdown of the average size of different property classes (also known as asset class or property type):
- Class A/A+ properties have an average size of 163,996 square feet.
- Class B properties are sized 93,547 square feet, on average.
- Class C properties span an average of 25,967 square feet.
The best area for commercial real estate in Durham will depend greatly on your needs. The neighborhood with the largest overall number of commercial listings is Research Triangle Park, home to no fewer than 173 listings for space of all types. If you're looking for office space, Research Triangle Park has the highest concentration of office listings at 151.

Meanwhile, Research Triangle Park has the highest number of industrial availabilities (11), while Downtown Durham boasts the largest number of retail listings in the city (18).
CommercialCafe’s CRE offering in Durham is enabled by a network of 165 active brokers from 73 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Asking rents in the city can be as high as $70.83 per square foot. In particular, the property type commanding the highest lease rates in Durham is Retail space.
The average size of a commercial property here stands at 1,067,864. However, different asset classes and zoning laws will result in vastly different property sizes. Here is a breakdown of the average size of different commercial asset classes in Durham:
Office properties:
- Average size: 95,815 square feet.
- Largest property: Space Available (260,000 square feet).
Retail properties:
- Average size: 77,388 square feet.
- Largest property: #1 (45,495 square feet).
Industrial properties:
- Average size: 109,540 square feet.
- Largest property: Space Available (846,010 square feet).

Durham, NC Commercial Space Listings

Commercial Space for Lease - Breakdown

The 256 listings for commercial real estate currently available for rent in Durham add up to 11,831,388 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	137	4,355,438
Retail	57	533,359
Industrial	44	5,874,726
Other	18	1,067,865

Office properties:

The market has 137 active office listings, encompassing 4,355,438 square feet.
Durham office spaces currently listed on CommercialCafe represent 53% of the total commercial real estate market in Durham, compared to an average of 39% across all markets tracked by CommercialCafe.

Retail Space:

There are 57 retail listings available, adding up to a total of 533,359 square feet.
Retail spaces account for approximately 22% of the local commercial market, while the average share taken up by retail in all U.S. markets is 34%.

Industrial Space:

The industrial market in Durham offers 44 listings, amounting to 5,874,726 available square feet.
Industrial spaces, including warehouses and manufacturing sites, make up about 17% of the total commercial space available in the market, compared to a nationwide average of 25%.

The data presented in this section was last updated as of September 10, 2026

Commercial Space for Sale - Breakdown

There are currently 58 properties listed for sale in the Durham market, adding up to 669,534 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

10 office properties
7 retail properties
7 industrial properties

The data presented in this section was last updated as of September 10, 2026

Property Type	Count of Listings	Total Sq. Ft.
Office	10	99,404
Retail	7	61,427
Industrial	7	470,656
Other	34	38,047

Durham, NC Commercial Real Estate Market Overview

The City of Durham is strategically located in the heart of North Carolina, thanks to Bartlett S. Durham — the man who donated his land for a railroad station, which laid the city’s initial foundation. At first, Durham thrived as a hub for the tobacco industry. Today, the city is a confluence of education, creativity, industry and innovation. Commercial real estate in Durham serves a diverse economy in which technology, healthcare and education are the main industries.

Along with Raleigh and Chapel Hill, Durham makes up what is commonly referred to as The Triangle — Raleigh-Durham-Chapel Hill Research Triangle Park or RTP for short — a high-tech research and development center that has greatly revitalized the region following deindustrialization. In addition to research and development, local commercial inventory caters to manufacturing activity; logistical and storage enterprise; and business services firms. Moreover, the several notable institutions of higher education located in the city produce a steady outflow of highly skilled talent, giving Durham one of the most concentrated STEM labor pools in the country.

Durham, NC Commercial Real Estate for Lease and Sale

Research Tri-Center North IV

4900 Prospectus Drive

411 Andrews Rd

1525 Glenn School Road

5112 Neal Rd

601 S Alston Ave

Triangle Meeting & Studio Space - 2603 South Miami Boulevard

7820 NC 751 Hwy

830 N Mangum St

University Hill

2202 East Geer Street

Frequently Asked Questions

Durham, NC Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

Durham, NC Commercial Real Estate Market Overview

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