Charleston, SC Commercial Real Estate for Lease and Sale
Explore 261 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
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1557 Meeting Street, Silver Hill - Magnolia, Charleston, SCProperty Type
- Office
For Sale- $3,700,000
Property size 6,228 SF -
1859 Summerville Avenue, Rosemont, North Charleston, SC
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123 Sportsman Island Drive, Daniel Island, Charleston, SCProperty Type
- VacantLand
For Sale- $800,000
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115 Fairchild Street, Daniel Island, SCSpace Type
- Office
For Lease- $29.95 - $32.00/SF/YR
5 spaces available / 2,157 - 8,762 SF -

What type of listing property are you looking for?
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174 Meeting Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $45.00/SF/YR
1 space available / 14,502 SF -
King Street Ext, Radcliffeborough, Charleston, SCProperty Type
- Other
For Sale- $675,000
Built in 2008 / Property size 800 SF -
1587 Savannah Hwy, Indigo Point - Harrison, Charleston, SCSpace Type
- Office
For Lease- $20.00/SF/YR
1 space available / 2,165 SF -
247 Rutledge Ave, Medical University of SC, Charleston, SCProperty Type
- Multi-Family
For Sale- $1,249,000
Built in 2014 / Property size 2,676 SF -
Whippoorwill Farm Rd, Harbor Woods - Bayview Farms, Johns Island, SC
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194 Seven Farms Drive, Daniel Island, Charleston, SC
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140 Spring Street, Medical University of SC, Charleston, SCProperty Type
- Other
For Sale- $2,995,000
Property size 3,028 SF -
170 Meeting Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $42.00 - $45.00/SF/YR
2 spaces available / 4,310 - 6,187 SF -
2585 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type
- Land
For Lease- $8,500.00/MO
1 space available / 65,775.6 SF -
2090 Executive Hall Rd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Office
For Lease- $18.00/SF/YR
1 space available / 850 SF -
115 Central Island St, Daniel Island, Charleston, SC
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3937 Savannah Hwy, Marsh View, Johns Island, SCSpace Type
- Office
For Lease- $7,000.00/MO
1 space available / 942 SF -
12 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type
- Office
For Lease- $16.00/SF/YR
1 space available / 1,954 SF -
2000 Sam Rittenberg Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Retail
For Lease- $25.00 - $32.00/SF/YR
4 spaces available / 1,100 - 2,315 SF -
170 Meeting Street Suite 200, Charleston, SCSpace Type
- Private Offices
For Lease-
From $424/month
Space for 1 to 50 people -
420 Brandam Lane, Daniel Island, Charleston, SCSpace Type
- Industrial
For Lease- $22.00 - $23.00/SF/YR
3 spaces available / 1,800 - 3,600 SF -
115 Fairchild Street Suite 100, Charleston, SCSpace Type
- Private Offices
For Lease-
From $414/month
Space for 1 to 15 people -
100 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type
- Office
For Lease- $43.00/SF/YR
1 space available / 9,675 SF -
720 Magnolia Road, Carolina Terrace - Magnolia, Charleston, SCSpace Type
- Retail
For Lease- $2,495.00/MO
1 space available / 1,315 SF -
234 Seven Farms Drive, Daniel Island, SCSpace Type
- Other
For Lease- $1,425.00/MO
1 space available / 293 SF -
215 Benefitfocus Way, Daniel Island, SC
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172 Ashley Avenue, Medical University of SC, Charleston, SCSpace Type
- Office
For Lease- $37.50/SF/YR
1 space available / 1,978 SF -
1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SCSpace Type
- Industrial
For Lease- $9.50/SF/YR
1 space available / 23,537 SF -
125 Fairchild Street, Daniel Island, Charleston, SCSpace Type
- Office
For Lease- $24.00 - $28.00/SF/YR
7 spaces available / 20,000 - 36,450 SF -
63 Montagu St, Harleston Village, Charleston, SCProperty Type
- Multi-Family
For Sale- $3,099,000
Built in 1922 / Property size 3,092 SF -
46 State St, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $36.00/SF/YR
1 space available / 1,500 SF -
61 Broad St, South of Broad, Charleston, SCProperty Type
- Office
For Sale- $2,700,000
Built in 1815 / Property size 7,058 SF -
1505 King Street, Silver Hill - Magnolia, Charleston, SC
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3874 Savannah Hwy, Northwest Charleston, Johns Island, SCSpace Type
- Retail
For Lease- $15.00/SF/YR
1 space available / 1,200 SF -
1045 5th Ave, Maryville - Asleyville, Charleston, SCSpace Type
- Industrial
For Lease- $21.00/SF/YR
1 space available / 4,200 SF -
2270 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SCSpace Type
- Office
For Lease- $32.00/SF/YR
1 space available / 3,746 SF -
2467 Savannah Hwy, Cherokee Hall - Sylvan Shores, Charleston, SC
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1470 Tobias Gadson Boulevard Ste 202, Charleston, SCSpace Type
- Private Offices
For Lease-
From $700/month
Space for 1 person -
Clements Ferry Rd, Daniel Island, Charleston, SCProperty Type- VacantLand
For Sale- $170,000
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284 Meeting St, Downtown Charleston, Charleston, SCProperty Type
- Office
For Sale- $1,650,000
Built in 2026 / Property size 1,600 SF -
2077 Charlie Hall Blvd, Essex Farms - Carolina Bay, Charleston, SCProperty Type
- Other
For Sale- $600,000
Property size 0.87 Acre -
1219 Hobart Avenue, Maryville - Asleyville, Charleston, SCProperty Type
- Office
For Sale- $990,000
Property size 2,567 SF -
2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC
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1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SCSpace Type
- Office
For Lease- $4,500.00/MO
1 space available / 2,702 SF -
850 Morrison Drive, Meeting St Manor - Cooper River Court, Charleston, SC
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901 Savannah Hwy, Bymes Downs - Coburg, Charleston, SC -
284 Meeting St, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $65.00/SF/YR
1 space available / 1,600 SF -
40 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type
- Office
For Lease- $1,100.00 - $1,450.00/MO
6 spaces available / 314 - 512 SF -
40 Line St, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Retail
For Lease- $35.00 - $55.00/SF/YR
4 spaces available / 930 - 8,479 SF -
125 Fairchild Street #200, Charleston, SCSpace Type
- Private Offices
For Lease-
From $539/month
Space for 1 to 15 people -
Clements Ferry Rd & Point Hope Pkwy, Daniel Island, Charleston, SC -
Ashley Hall Plantation Rd, Ashely Hall Plantation, Charleston, SC -
997 Morrison Drive #200, Charleston, SCSpace Type
- Private Offices
For Lease-
From $2,500/month
Space for 1 to 6 people -
18 Broad Street 1st-4th Floor, Charleston, SCSpace Type
- Private Offices
For Lease-
From $1,245/month