Charleston, SC Commercial Real Estate for Lease and Sale

Explore 261 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.

  • 1557 Meeting Street, Silver Hill - Magnolia, Charleston, SC
    Property Type
    • Office
    For Sale
    • $3,700,000
    Property size 6,228 SF
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  • 1859 Summerville Avenue, Rosemont, North Charleston, SC
    Space Type
    • Office
    3 spaces available / 968 - 2,996 SF
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  • 123 Sportsman Island Drive, Daniel Island, Charleston, SC
    Property Type
    • VacantLand
    For Sale
    • $800,000
    View Details
  • 115 Fairchild Street, Daniel Island, SC
    Space Type
    • Office
    For Lease
    • $29.95 - $32.00/SF/YR
    5 spaces available / 2,157 - 8,762 SF
    View Details
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  • 174 Meeting Street, Downtown Charleston, Charleston, SC
    Space Type
    • Office
    For Lease
    • $45.00/SF/YR
    1 space available / 14,502 SF
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  • King Street Ext, Radcliffeborough, Charleston, SC
    Property Type
    • Other
    For Sale
    • $675,000
    Built in 2008 / Property size 800 SF
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  • 1587 Savannah Hwy, Indigo Point - Harrison, Charleston, SC
    Space Type
    • Office
    For Lease
    • $20.00/SF/YR
    1 space available / 2,165 SF
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  • 247 Rutledge Ave, Medical University of SC, Charleston, SC
    Property Type
    • Multi-Family
    For Sale
    • $1,249,000
    Built in 2014 / Property size 2,676 SF
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  • Whippoorwill Farm Rd, Harbor Woods - Bayview Farms, Johns Island, SC
    Property Type
    • VacantLand
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  • 194 Seven Farms Drive, Daniel Island, Charleston, SC
    Space Type
    • Office
    1 space available / 10,419 SF
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  • 140 Spring Street, Medical University of SC, Charleston, SC
    Property Type
    • Other
    For Sale
    • $2,995,000
    Property size 3,028 SF
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  • 170 Meeting Street, Downtown Charleston, Charleston, SC
    Space Type
    • Office
    For Lease
    • $42.00 - $45.00/SF/YR
    2 spaces available / 4,310 - 6,187 SF
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  • 2585 Clements Ferry Rd, Daniel Island, Charleston, SC
    Space Type
    • Land
    For Lease
    • $8,500.00/MO
    1 space available / 65,775.6 SF
    View Details
  • 2090 Executive Hall Rd, Savage Road - Citadel Mall, Charleston, SC
    Space Type
    • Office
    For Lease
    • $18.00/SF/YR
    1 space available / 850 SF
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  • 115 Central Island St, Daniel Island, Charleston, SC
    Space Type
    • Office
    2 spaces available / 8,945 - 11,101 SF
    View Details
  • 3937 Savannah Hwy, Marsh View, Johns Island, SC
    Space Type
    • Office
    For Lease
    • $7,000.00/MO
    1 space available / 942 SF
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  • 12 Farmfield Ave, Parkwood - Farmfield, Charleston, SC
    Space Type
    • Office
    For Lease
    • $16.00/SF/YR
    1 space available / 1,954 SF
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  • 2000 Sam Rittenberg Blvd, Savage Road - Citadel Mall, Charleston, SC
    Space Type
    • Retail
    For Lease
    • $25.00 - $32.00/SF/YR
    4 spaces available / 1,100 - 2,315 SF
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  • 170 Meeting Street Suite 200, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $424/month
    Space for 1 to 50 people
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  • 420 Brandam Lane, Daniel Island, Charleston, SC
    Space Type
    • Industrial
    For Lease
    • $22.00 - $23.00/SF/YR
    3 spaces available / 1,800 - 3,600 SF
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  • 115 Fairchild Street Suite 100, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $414/month
    Space for 1 to 15 people
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  • 100 Calhoun Street, Mazyck - Wraggborough, Charleston, SC
    Space Type
    • Office
    For Lease
    • $43.00/SF/YR
    1 space available / 9,675 SF
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  • 720 Magnolia Road, Carolina Terrace - Magnolia, Charleston, SC
    Space Type
    • Retail
    For Lease
    • $2,495.00/MO
    1 space available / 1,315 SF
    View Details
  • 234 Seven Farms Drive, Daniel Island, SC
    Space Type
    • Other
    For Lease
    • $1,425.00/MO
    1 space available / 293 SF
    View Details
  • 215 Benefitfocus Way, Daniel Island, SC
    Space Type
    • Office
    4 spaces available / 36,450 SF
    View Details
  • 172 Ashley Avenue, Medical University of SC, Charleston, SC
    Space Type
    • Office
    For Lease
    • $37.50/SF/YR
    1 space available / 1,978 SF
    View Details
  • 1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SC
    Space Type
    • Industrial
    For Lease
    • $9.50/SF/YR
    1 space available / 23,537 SF
    View Details
  • 125 Fairchild Street, Daniel Island, Charleston, SC
    Space Type
    • Office
    For Lease
    • $24.00 - $28.00/SF/YR
    7 spaces available / 20,000 - 36,450 SF
    View Details
  • 63 Montagu St, Harleston Village, Charleston, SC
    Property Type
    • Multi-Family
    For Sale
    • $3,099,000
    Built in 1922 / Property size 3,092 SF
    View Details
  • 46 State St, Downtown Charleston, Charleston, SC
    Space Type
    • Office
    For Lease
    • $36.00/SF/YR
    1 space available / 1,500 SF
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  • 61 Broad St, South of Broad, Charleston, SC
    Property Type
    • Office
    For Sale
    • $2,700,000
    Built in 1815 / Property size 7,058 SF
    View Details
  • 1505 King Street, Silver Hill - Magnolia, Charleston, SC
    Space Type
    • Retail
    4 spaces available / 2,227 - 6,341 SF
    View Details
  • 3874 Savannah Hwy, Northwest Charleston, Johns Island, SC
    Space Type
    • Retail
    For Lease
    • $15.00/SF/YR
    1 space available / 1,200 SF
    View Details
  • 1045 5th Ave, Maryville - Asleyville, Charleston, SC
    Space Type
    • Industrial
    For Lease
    • $21.00/SF/YR
    1 space available / 4,200 SF
    View Details
  • 2270 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SC
    Space Type
    • Office
    For Lease
    • $32.00/SF/YR
    1 space available / 3,746 SF
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  • 2467 Savannah Hwy, Cherokee Hall - Sylvan Shores, Charleston, SC
    Space Type
    • Industrial
    1 space available / 3,704 SF
    View Details
  • 1470 Tobias Gadson Boulevard Ste 202, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $700/month
    Space for 1 person
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  • VacantLand space for Sale at Clements Ferry Rd in Charleston
    Clements Ferry Rd, Daniel Island, Charleston, SC
    Property Type
    • VacantLand
    For Sale
    • $170,000
    View Details
  • 284 Meeting St, Downtown Charleston, Charleston, SC
    Property Type
    • Office
    For Sale
    • $1,650,000
    Built in 2026 / Property size 1,600 SF
    View Details
  • 2077 Charlie Hall Blvd, Essex Farms - Carolina Bay, Charleston, SC
    Property Type
    • Other
    For Sale
    • $600,000
    Property size 0.87 Acre
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  • 1219 Hobart Avenue, Maryville - Asleyville, Charleston, SC
    Property Type
    • Office
    For Sale
    • $990,000
    Property size 2,567 SF
    View Details
  • 2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC
    Space Type
    • Industrial
    1 space available / 91,520 SF
    View Details
  • 1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SC
    Space Type
    • Office
    For Lease
    • $4,500.00/MO
    1 space available / 2,702 SF
    View Details
  • 850 Morrison Drive, Meeting St Manor - Cooper River Court, Charleston, SC
    Space Type
    • Office
    7 spaces available / 1,627 - 12,852 SF
    View Details
  • Retail space for Rent at 901 Savannah Hwy in Charleston
    901 Savannah Hwy, Bymes Downs - Coburg, Charleston, SC
    Space Type
    • Retail
    3 spaces available / 1,164 - 7,500 SF
    View Details
  • 284 Meeting St, Downtown Charleston, Charleston, SC
    Space Type
    • Office
    For Lease
    • $65.00/SF/YR
    1 space available / 1,600 SF
    View Details
  • 40 Calhoun Street, Mazyck - Wraggborough, Charleston, SC
    Space Type
    • Office
    For Lease
    • $1,100.00 - $1,450.00/MO
    6 spaces available / 314 - 512 SF
    View Details
  • 40 Line St, Cannonborough - Elliottborough, Charleston, SC
    Space Type
    • Retail
    For Lease
    • $35.00 - $55.00/SF/YR
    4 spaces available / 930 - 8,479 SF
    View Details
  • 125 Fairchild Street #200, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $539/month
    Space for 1 to 15 people
    View Details
  • Other space for Sale at Clements Ferry Rd & Point Hope Pkwy in Charleston
    Clements Ferry Rd & Point Hope Pkwy, Daniel Island, Charleston, SC
    Property Type
    • Other
    View Details
  • Other space for Sale at Ashley Hall Plantation Rd in Charleston
    Ashley Hall Plantation Rd, Ashely Hall Plantation, Charleston, SC
    Property Type
    • Other
    View Details
  • 997 Morrison Drive #200, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $2,500/month
    Space for 1 to 6 people
    View Details
  • 18 Broad Street 1st-4th Floor, Charleston, SC
    Space Type
    • Private Offices
    For Lease
    • From $1,245/month
    View Details