Charleston, SC Commercial Real Estate for Lease and Sale
Explore 261 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
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2225 Ashley Crossing Drive, Pierpont, Charleston, SCSpace Type- Office
For Lease- $25.00/SF/YR
2 spaces available / 700 SF -
2049 Savannah Highway , Air Harbor - Geddes Hall, Charleston, SCSpace Type- Retail
For Lease- $20.00/SF/YR
1 space available / 12,000 SF -
2030 Wambaw Creek Road, Daniel Island, Charleston, SCSpace Type- Retail
For Lease- $16.00 - $17.00/SF/YR
2 spaces available / 2,820 - 3,973 SF -
561 & 563 King Street, Cannonborough - Elliottborough, Charleston, SCProperty Type- Retail
For Sale- $32,500,000
Property size 33,678 SF -

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125 Wappoo Creek Dr, Wappoo Creek - McLeod Plantation, Charleston, SCSpace Type- Office
For Lease- $18.00 - $23.00/SF/YR
2 spaces available / 1,540 - 2,200 SF -
2245 Clements Ferry Rd, Daniel Island, Charleston, SC -
14 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type- Office
For Lease- $28.00/SF/YR
3 spaces available / 2,895 - 3,741 SF -
635 King Street, Cannonborough - Elliottborough, Charleston, SC -
635 Rutledge Avenue, Charleston, SC -
563 King St, Cannonborough - Elliottborough, Charleston, SC -
148 1/2 Cannon Street, Medical University of SC, Charleston, SCSpace Type- Special Purpose
For Lease- $67.61/SF/YR
1 space available / 355 SF -
207 Rutledge Ave, Medical University of SC, Charleston, SC -
478 King St, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $1,500.00 - $1,800.00/MO
5 spaces available / 270 - 395 SF -
15 Gamecock Ave, Sandhurst - Governours Point, Charleston, SCSpace Type- Office
For Lease- $26.00 - $41.67/SF/YR
2 spaces available / 720 - 3,625 SF -
89 Hanover St, East Side Charleston, Charleston, SC -
1029 St Andrews Blvd, Maryville - Asleyville, Charleston, SCSpace Type- Retail
For Lease- $25.00/SF/YR
1 space available / 3,600 SF -
1365 Ashley River Rd, St. Andrews - Forest, Charleston, SCSpace Type- Office
For Lease- $24.00/SF/YR
2 spaces available / 826 - 1,217 SF -
12 Queen Street, Harleston Village, Charleston, SCProperty Type- Retail
For Sale- $1,200,000
Property size 1,010 SF -
95 Cannon St, Cannonborough - Elliottborough, Charleston, SC -
119-B Thomas Cary Court, Daniel Island, Charleston, SCSpace Type- Industrial
For Lease- $4,250.00/MO
1 space available / 2,400 SF -
241 - 243 East Bay Street, Downtown Charleston, Charleston, SCProperty Type- Multi-Family
For Sale- $6,500,000
Built in 1871 / Property size 9,876 SF -
95 Folly Road Boulevard, Crescent - Albemarie Point, Charleston, SCSpace Type- Mixed Use
For Lease- $30,000.00/MO
1 space available / 17,855 SF -
11 Cannon St, Cannonborough - Elliottborough, Charleston, SC -
100 Cool Blow Street, East Central Charleston, Charleston, SCSpace Type- Office
For Lease- $42.00/SF/YR
1 space available / 1,000 SF -
2386 Clements Ferry Road, Daniel Island, Wando, SC -
13-15 Cannon Street, Cannonborough - Elliottborough, Charleston, SC -
866 Island Park Drive, Daniel Island, Charleston, SC -
335 King St, Downtown Charleston, Charleston, SC -
1014 St. Andrews Blvd, Maryville - Asleyville, Charleston, SCSpace Type- Office
For Lease- $33.75/SF/YR
4 spaces available / 1,800 - 9,505 SF -
9 Linguard St, Downtown Charleston, Charleston, SC -
1300 Savannah Highway, St. Andrews - Forest, Charleston, SCSpace Type- Retail
For Lease- $28.00 - $30.00/SF/YR
2 spaces available / 1,250 - 1,600 SF -
2026 Meeting Street Rd, Four Mile Hibernian, Charleston, SCSpace Type- Industrial
For Lease- $17,500.00/MO
1 space available / 4,000 SF -
2637 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type- Land
For Lease- $7,500.00/Acre/MO
1 space available / 87,120 SF -
716 Meeting St, East Central Charleston, Charleston, SCSpace Type- Retail
For Lease- $45.00/SF/YR
1 space available / 1,250 SF -
835 Savannah Highway 2nd Floor, Charleston, SC -
176 Croghan Spur Rd, Crescent - Albemarie Point, Charleston, SC -
852 Orleans Rd, Dupont Area - Orleans, Charleston, SC -
612 Hunt Club, Village Square - Pinecrest Gardens, West Ashley, SC -
1332 Ashley River Rd, Old Town Acres - Plantation Basin, Charleston, SC -
2 Radcliffe St, Radcliffeborough, Charleston, SCSpace Type- Retail
For Lease- $42.00/SF/YR
1 space available / 5,095 SF -
109 River Landing Dr, Daniel Island, Charleston, SC -
3865 West Ashley Circle, Mt Royall - Harrington Place, Charleston, SC -
1505 King Street Ext, Silver Hill - Magnolia, North Charleston, SCSpace Type- Office
For Lease- $39.00/SF/YR
1 space available / 7,738 SF -
1238 Camp Road, Whitehouse Plantation - Creek Point, Charleston, SCSpace Type- Retail
For Lease- $18.00/SF/YR
1 space available / 4,255 SF -
11 Isabella Street, East Central Charleston, Charleston, SCSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 1,650 SF -
149 E Bay St, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $19.50/SF/YR
2 spaces available / 2,375 - 2,700 SF -
1701 Charleston Regional Parkway, Charleston, SC -
Bear Swamp Rd, Northwest Charleston, Johns Island, SCProperty Type- VacantLand
For Sale- $315,000
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1159 Cainhoy Rd, Daniel Island, Charleston, SCSpace Type- Industrial
For Lease- $15.50 - $4,000.00/SF/YR
2 spaces available / 1 - 12,000 SF -
119 Spring Street, Medical University of SC, Charleston, SCProperty Type- Retail
For Sale- $7,750,000
Property size 12,000 SF -
3865 West Ashley Circle, Mt Royall - Harrington Place, Charleston, SCSpace Type- Retail
For Lease- $42.00/SF/YR
2 spaces available / 1,500 - 2,500 SF -
151 Market Street, Harleston Village, Charleston, SCSpace Type- Retail
For Lease- $37.00/SF/YR
1 space available / 1,945 SF -
2003 Cherry Hill Ln, Four Mile Hibernian, North Charleston, SC