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62 Office Spaces for Rent in Saint Charles, MO

  • SSM Health Medical Buildings 1 & 2 - St. Charles
    330 1st Capitol Drive, St. Charles, MO
    For Lease
    • $24.5 - $28/SF/YR
    Property
    • Office
    • 81,400 SF
    Availability
    • 7 Spaces
    • 11,804 SF
    Year Built
    • 1987
    View Details
  • 1551 Wall Street - St. Charles
    1551 Wall Street, St. Charles, MO
    For Lease
    • Contact for pricing
    Property
    • Office
    • 77,000 SF
    Availability
    • 4 Spaces
    • 26,157 SF
    Year Built
    • 2000
    View Details
  • Executive Centre II - St. Peters
    5650 Mexico Road, City Center Park, St. Peters, MO
    For Lease
    • $20/SF/YR
    Property
    • Office
    • 31,848 SF
    Availability
    • 3 Spaces
    • 7,542 SF
    Year Built
    • 1996
    View Details
  • 3513 Harry S Truman Blvd - St. Charles
    3513 Harry S Truman Blvd, St. Charles, MO
    For Lease
    • $17/SF/YR
    Property
    • Office
    • 12,000 SF
    Availability
    • 1 Space
    • 6,000 SF
    Year Built
    • 2020
    View Details
  • 1000 Technology Drive - O'Fallon
    1000 Technology Drive, Weldon Spring, O'fallon, MO
    For Lease
    • Contact for pricing
    Property
    • Office
    • 518,601 SF
    Availability
    • 2 Spaces
    • 126,000 SF
    Year Built
    • 2002
    View Details
  • 14 Research Park Dr - Saint Charles
    14 Research Park Dr, Howell Island Conservation Area, Saint Charles, MO
    For Lease
    • $19.5/SF/YR
    Property
    • Office
    • 10,568 SF
    Availability
    • 1 Space
    • 10,568 SF
    Year Built
    • 1994
    View Details
  • 370 Corporate Center - St. Charles
    3000 Little Hills Expwy, St. Charles, MO
    For Lease
    • $15.75/SF/YR
    Property
    • Office
    • 131,191 SF
    Availability
    • 1 Space
    • 10,000 SF
    Year Built
    • 1998
    View Details
  • Three Flags Business Center - St. Charles
    1360 South 5th Street, St. Charles, MO
    For Lease
    • $14 - $16/SF/YR
    Property
    • Office
    • 61,754 SF
    Availability
    • 11 Spaces
    • 13,180 SF
    Year Built
    • 1972
    View Details
  • Compass Point Dr. Saint Charles - Saint Charles
    226 Compass Point Dr. Saint Charles, Saint Charles, MO
    For Lease
    • $13.5/SF/YR
    Property
    • Office
    • 17,800 SF
    Availability
    • 1 Space
    • 5,000 SF
    Year Built
    • 1987
    View Details
  • 3569 New Town Lake Drive - Saint Charles
    3569 New Town Lake Dr, Saint Charles, MO
    For Lease
    • $2,950/MO
    Property
    • Office
    • 5,166 SF
    Availability
    • 1 Space
    • 2,563 SF
    Year Built
    • 2006
    View Details
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  • Harmsted Industrial Ct. - Saint Charles
    951-961 Harmsted Ct., Saint Charles, MO
    For Lease
    • $7.25/SF/YR
    Property
    • Industrial
    • 31,130 SF
    Availability
    • 1 Space
    • 11,670 SF
    Year Built
    • 1996
    View Details
  • Enterprise Technology Center - Saint Charles
    600-620 Technology Drive, Weldon Spring, Saint Charles, MO
    For Lease
    • $22/SF/YR
    Property
    • Office
    • 138,092 SF
    Availability
    • 4 Spaces
    • 101,939 SF
    View Details
  • 4618 South St Peters Pkwy - Saint Charles
    4618 S St Peters Pkwy, Saint Charles, MO
    For Lease
    • $12.95 - $19.8/SF/YR
    Property
    • Retail
    • 18,000 SF
    Availability
    • 2 Spaces
    • 4,800 SF
    Year Built
    • 2003
    View Details
  • 2040 Campus Dr - Saint Charles
    2040 Campus Dr, Saint Charles, MO
    For Lease
    • $14/SF/YR
    Property
    • Mixed Use
    • 6,680 SF
    Availability
    • 4 Spaces
    • 3,080 SF
    Year Built
    • 1975
    View Details
  • 2801 Veterans Memorial Parkway - Saint Charles
    2801 Veterans Memorial Parkway, Saint Charles, MO
    For Lease
    • $19.5/SF/YR
    Property
    • Retail
    • 6,948 SF
    Availability
    • 1 Space
    • 6,948 SF
    View Details
  • 95 Arco Drive - St. Charles
    95 Arco Drive, St. Charles, MO
    For Lease
    • Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 763 SF
    View Details
  • 333 1st Capitol Dr - Saint Charles
    333 1st Capitol Dr, Saint Charles, MO
    For Lease
    • $18/SF/YR
    Property
    • Office
    • 5,880 SF
    Availability
    • 1 Space
    • 2,807 SF
    Year Built
    • 1986
    View Details
  • 620 Technology Drive - Weldon Spring
    620 Technology Drive, Weldon Spring, MO
    For Lease
    • $22/SF/YR
    Property
    • Office
    • 138,092 SF
    Availability
    • 5 Spaces
    • 120,432 SF
    View Details
  • 36,419 RSF Office Sublease Located in the Streets of St. Charles - Frontier Township
    1450 Beale St, Frontier Township, MO
    For Lease
    • Contact for pricing
    Property
    • Office
    Availability
    • 1 Space
    • 36,419 SF
    Year Built
    • 2019
    View Details
  • 1811 Sherman Dr - Saint Charles
    1811 Sherman Dr, Saint Charles, MO
    For Lease
    • $14 - $15/SF/YR
    Property
    • Office
    • 11,287 SF
    Availability
    • 3 Spaces
    • 4,970 SF
    Year Built
    • 1985
    View Details
  • 2046 Queens Brooke Blvd - St. Peters
    2046 Queens Brooke Blvd, St. Peters, MO
    For Lease
    • $375/MO
    Property
    • Office
    • 9,920 SF
    Availability
    • 1 Space
    • 180 SF
    View Details
  • 2300 Highway 94 South Outer Rd - Saint Charles
    2300 Highway 94 South Outer Rd, Saint Charles, MO
    For Lease
    • $10 - $13.5/SF/YR
    Property
    • Office
    • 7,500 SF
    Availability
    • 3 Spaces
    • 5,500 SF
    Year Built
    • 1998
    View Details
  • Streets Of St. Charles - 1650 Beale Street - Saint Charles
    1650 Beale Street, Saint Charles, MO
    For Lease
    • $22/SF/YR
    Property
    • Office
    • 1,606 SF
    Availability
    • 1 Space
    • 1,606 SF
    View Details
  • 15 Research Park Drive - St. Charles
    Off Market
    15 Research Park Drive, Howell Island Conservation Area, St. Charles, MO
    Property
    • Office
    • 50,846 SF
    Year Built
    • 2004
  • 3050 West Clay Street - St. Charles
    Off Market
    3050 West Clay Street, St. Charles, MO
    Property
    • Office
    • 34,200 SF
    Year Built
    • 2008
  • Missouri Research Park - 36 Research Park Court - St. Charles
    Off Market
    36 Research Park Court, Howell Island Conservation Area, St. Charles, MO
    Property
    • Office
    • 81,125 SF
    Year Built
    • 2007

Saint Charles, MO Office Space Listings

There are currently 50 office listings available in Saint Charles, MO. These listings include 62 office spaces that encompass a total of 497,902 square feet. Available office spaces in Saint Charles, MO range in size from 180 square feet to 63,000 square feet. A total of 26 off-market office properties located in Saint Charles, MO are also available for research.

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Are you still looking for the office space near you that’s perfect for your business? Browse through all available CommercialCafe listings in your area to find the right fit — the space that meets your requirements, right now and for the future. Easily compare sizes, prices, amenities and locations of office spaces for rent near me. Expand your search beyond your neighborhood and ZIP code and search our listings in any city or state to find the best fit for your needs, wherever you are in the U.S. The perfect office space for rent near Saint Charles, MO is only one search away.

Saint Charles, MO Office Inventory Breakdown

Office Spaces

Total: 2,908,840 SF

Data provided by Yardi Matrix, properties over 50k SF, includes office with retail
By square footage range:
50k to 100k SqFt 999,048 SqFt 34.35% of total office
100k to 500k SqFt 1,391,191 SqFt 47.83% of total office
500k to 1M SqFt 518,601 SqFt 17.83% of total office
By class:
Class A 1,447,012 SqFt 49.75% of total office
Class B 1,149,828 SqFt 39.53% of total office
Class C 60,000 SqFt 2.06% of total office
In 2022 the Saint Charles, MO office market encompassed 2,908,840 square feet of space. Of these, 518,601 square feet were office properties between 500K to 1M square feet and 999,048 square feet were buildings between 50k to 100k.

Class A office space makes up a 49.75% share of Saint Charles, MO office inventory, while Class B office assets represent roughly 39.53%.

Frequently Asked Questions

How much does office space cost in Saint Charles, MO?

The average office rental rate in Saint Charles, MO is $22.61 per square foot. Asking prices vary based on the property’s location, overall rating, amenities, proximity to restaurants, cafes and entertainment venues, as well as public transport, airports and highways. Check Saint Charles Office Market Trends for more stats.

What is the size of available office spaces in Saint Charles, MO?

The Saint Charles, MO office market can accommodate various businesses, sporting a range of office space availabilities. The average size of office space availabilities is 31,590 square feet. If you’re just starting out as a company or as an entrepreneur, the smallest available office space in Saint Charles, MO is 180 square feet, while the maximum rentable space on the market now is 63,000 square feet.

How do I get office space in Saint Charles, MO?

Start your search for office space in Saint Charles, MO by using our filters that allow you to find the best space for your business needs. Filter listings by location, property size, available space or lease rate. Property pages will offer details about an office building’s rating, year built, availabilities, price per square foot and more. After drawing up a shortlist, make sure you contact the listed broker(s) to schedule a viewing and begin the negotiation process for your lease contract.

How many office listings are available in Saint Charles, MO?

There are 50 office listings on the Saint Charles, MO market. See all available office spaces for rent.

Where to rent an office space in Saint Charles, MO?

Popular Saint Charles neighbourhoods with available office spaces include and City Center Park.

What other property types are available for lease in Saint Charles, MO?

In addition to traditional office spaces, commercial real estate listings on our platform also include coworking & shared office space options, retail spaces, industrial buildings, warehouses, distribution facilities, and more.