Brentwood, MO Office Spaces for Rent

Find the best Brentwood, MO office space among 29 for rent listings currently on the market.

The Meridian at Brentwood

8300 Eager Road, Brentwood, St. Louis, MO
Property Type

Office
For Lease

$28.50/SF/YR
7 spaces available / 6,497 - 26,473 SF
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The Milton Building

2025 South Brentwood Blvd, Brentwood, MO
Property Type

Office
For Lease

$23.00/SF/YR
1 space available / 4,707 SF
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The Meridian at Brentwood - 1405-1413 South Hanley Road

1405 South Hanley Road, Brentwood, St. Louis, MO
Property Type

Office
For Lease

$28.50/SF/YR
2 spaces available / 15,000 SF
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Center 40

1600 South Brentwood Blvd, Brentwood, St. Louis, MO
Property Type

Office
For Lease Contact for pricing

5 spaces available / 2,998 - 14,028 SF
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8760, 8764, 8770, 8780, 8790 & 8798 Manchester Road

8760 Manchester Road, Brentwood, St. Louis, MO
Property Type

Office
For Lease

$16.50 - $21.00/SF/YR
2 spaces available / 1,015 - 1,555 SF
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8700 Manchester Rd

8700 Manchester Rd, Brentwood, Saint Louis, MO
Property Type

Office
For Lease

$22.50/SF/YR
4 spaces available / 1,381 - 3,623 SF
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1300 Strassner Drive

1300 Strassner Drive, Brentwood, MO
Property Type

Office
For Lease

$12.00/SF/YR
1 space available / 5,515 SF
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Hanley Pointe

2001 S Hanley Road, Brentwood, Saint Louis, MO
Property Type

Office
For Lease

$18.50/SF/YR
8 spaces available / 800 - 5,262 SF
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8374 Eager Road

8374 Eager Road, Brentwood, MO
Property Type

Office
For Lease

$25.00/SF/YR
1 space available / 70,000 SF
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516 Hanley Industrial Court
Nexus Coworking
516 Hanley Industrial Court, Brentwood, MO
Property Type

Private Offices
For Lease

From $899/month
Space for 1 to 10 people
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The minimum rental rate for office space in Brentwood is $18.5 per square foot. Among listings of office space currently available for lease in Brentwood, the maximum rental rate is $25 per square foot.
Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Brentwood, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 70,000 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in Brentwood is 4,083 square feet, and the average office space size here is 9,251 square feet.
You can find 29 office listing(s) for lease in Brentwood, which add up to a total of 292,519 square feet. Availability on the market includes a variety of office use types, such as General Office.

The most common office use type currently available for lease in Brentwood is General Office, which is offered in 15 or 51.72% of listings.
Sublease opportunities on the market include General Office.
The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.
Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.
The Brentwood office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 20.69% of total office space listings in the city are in properties rated Class A. Class B office space accounts for 68.97% of spaces listed on the leasing market. Class C office space makes up 6.9% of office space available in Brentwood.

Buildings completed in and since the year 2000 account for 22.22% of office properties in the city and incorporate a total of 252,507 square feet.
There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.
Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Brentwood? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Brentwood, MO Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Brentwood: 1,007,552 Sq. Ft.

In 2025 the Brentwood office market encompassed 1,007,552 square feet of space.
Class A office space makes up a 37.36% share of Brentwood office inventory, while Class B office assets represent roughly 50.57% of the market total.

Brentwood Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	161,622 Sq. Ft.	16.04%
100k to 500k Sq. Ft.	492,064 Sq. Ft.	48.84%

Brentwood Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	376,437 Sq. Ft.	37.36%
Class B	509,549 Sq. Ft.	50.57%
Class C	92,569 Sq. Ft.	9.19%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

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Brentwood, MO Office Spaces for Rent

The Meridian at Brentwood

The Milton Building

The Meridian at Brentwood - 1405-1413 South Hanley Road

Center 40

8760, 8764, 8770, 8780, 8790 & 8798 Manchester Road

8700 Manchester Rd

1300 Strassner Drive

Hanley Pointe

8374 Eager Road

516 Hanley Industrial Court

Frequently Asked Questions

Brentwood, MO Office Inventory Breakdown

Total Office Space in Brentwood: 1,007,552 Sq. Ft.

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