Durham, NC Office Spaces for Rent

Find your best Durham, NC office space among 457 for rent listings, which average an asking price of $33.69 per square foot.

Office Market FAQs

American Underground - 324 Blackwell Street

324 Blackwell Street #900, Durham, NC
Space Type

Private Offices
For Lease

Contact for pricing
View Details
Pine Ridge Office Centre

6015 & 6011 Fayetteville Rd, Crooked Creek, Durham, NC
Space Type

Office
For Lease

$16.00/SF/YR
1 space available / 800 SF
View Details
One RTP Tower

4130 Sancar Way, Research Triangle Park, NC
Space Type

Office
For Lease Contact for pricing

9 spaces available / 30,000 SF
View Details
Locale321 - 321 East Chapel Hill Street

321 East Chapel Hill Street, Durham, NC
Space Type

Private Offices
For Lease

Contact for pricing
Space for 1 to 6 people
View Details
Bentley Ridge

5607 & 5611 NC 55, Audubon Park, Duham, NC
Space Type

Office
For Lease

$18.00 - $24.00/SF/YR
4 spaces available / 847 - 1,416 SF
View Details
Brassfield IV

4528 Hillsborough Rd, West Hills, Durham, NC
Space Type

Office
For Lease

$20.00/SF/YR
1 space available / 750 SF
View Details

Frequently Asked Questions

In Durham, office spaces range from smaller units to larger options. On average, office spaces in this area tend to be about 9,914 square feet. However, the largest listings can go up to 260,000 square feet for an individual listing. This can give you a good starting point to compare with your needs.
In Durham, you have several options when it comes to leasing office space. To better understand what to look for, check out our definitive guide to finding office space for your small business or startup. Here is an overview of the most common types currently available:
- Most Common Office Type
  The most frequent subtype available for lease is General Office, which makes up 54.70% of all listings in the city.
- Second-Most Common Office Type
  The second-most common office space type listed here is Life Sciences, accounting for 7.22% of available listings.
- Third-Most Common Office Type
  Up next, Creative Office also makes up a significant portion of listings, offering additional options for those seeking alternative spaces.
- Rarest Office Type
  On the other end of the spectrum, the rarest type of office space among local listings is Street Retail, with only 1 listing currently available.
You can find a total of 457 listings for lease in Durham, which add up to a total of 4.4 million square feet. Out of these listings, 30 are sublease listings, with the highest concentration of sublease listings being located in Research Triangle Park
Generally, buildings completed since the year 2000 offer modern amenities, decor and services. This also applies to buildings that have been renovated within the same timeframe. Buildings completed in or after the year 2000 account for 18.25% of office properties in this city and incorporate a total of 3,076,325 square feet. Additionally, about 3.65% of office space in Durham is in buildings that have been renovated at least once since 2000.

Durham, NC Office Space for Rent

Office inventory

According to our listing data, Durham's office market contains 28M square feet of space as of 2026.

Durham Office Market Breakdown by Building Size
Building Size Range	Total Square Feet
50k to 100k Sq. Ft.	5.8M Sq. Ft.
100k to 500k Sq. Ft.	13.7M Sq. Ft.
500k to 1M Sq. Ft.	1.2M Sq. Ft.
> 1M Sq. Ft.	4.7M Sq. Ft.

Data was provided by Yardi Research Data, refers to properties larger than 50,000 square feet.

Properties sized 100k to 500k Sq. Ft. make up most of the local office inventory, amounting to 13.7M square feet.

Average Rent for Office Spaces

The average rent for office space in Durham is $27 per square foot. However, you can find rental rates as low as $11 per square foot here, depending on what compromises you are willing to make. If you are looking for office space priced at a certain value, you can use the filters at the top of the page to look for properties within your optimal range.

The maximum rental rate is $71 per square foot among local listings currently available for lease.

For our detailed analysis of the latest rent and sale prices in Durham, as well as overall market quality and new construction data, see Durham Office Market Trends.

Office Spaces Classes

The office space market in Durham incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. 51.78% of total office listings in this city are in properties rated Class A. Class B accounts for 43.41% of traditional work spaces listed on the leasing market. Class C makes up 4.81% of such listings in Durham. This data is current as of 2026.

Durham Office Market Breakdown by Building Class
Class	Total Square Feet	Share of Total Office
A	14.5M	51.78%
B	12.1M	43.41%
C	1.3M	4.81%

Data was provided by Yardi Research Data, refers to properties larger than 50,000 square feet.

The most common factor that influences the cost of renting space for your business in any location is the property class rating. For example, Durham office space rated Class A asks an average of $30.03 per square foot. Class B space in Durham costs $26.46 per square foot, on average. Listings of available space in Class C buildings asked an average of $15.98 per square foot.

Top Neighborhoods for Office Space

Location is everything when it comes to office spaces. Tenants place great value on well positioned properties in amenity-rich areas, potentially boosting office attendance.

In Durham, the greatest concentration of lease opportunities is in Research Triangle Park, Copper Creek and Downtown Durham.

Office Classes in Durham, North Carolina Neighborhoods

Research Triangle Park

Downtown Durham

Central Park

Class A+/A
Class B
Class C

The Research Triangle Park neighborhood contains the most Class A office space, attracting premium tenants and corporate headquarters. Meanwhile, the neighborhood with the most Class B space is Research Triangle Park, offering quality space at affordable rates.

Durham, NC Office Market Overview

Located in the heart of North Carolina, the City of Durham began as a railroad station and grew into a hub for the tobacco industry, followed by more growth due to the expansion of the textile and electric power industries. Today, Durham is an educational, medical, and research center at the confluence of creativity, industry and innovation. Notably, the current stock of office space in Durham is, to a significant extent, the result of several conversions of large-block historical properties left behind by the tobacco industry. The ambitious, large-scale renovations turned historic factories into offices, condominiums and restaurants, thereby reshaping the city’s central business district toward a future-facing economic strategy.

Outside of downtown, most of the development in the last few decades has been along the I-40 corridor. Office space here encompasses both traditional and flexible workspace models, and benefits from a wide array of high-quality amenities, as well as great connectivity to all major points of interest in the region. However, perhaps the most notable aspect of Durham is its inclusion in the Raleigh-Durham-Chapel Hill Research Triangle Park (“The Triangle” or “RTP” for short) — a great regional collaboration that created a high-tech research and development center unlike any other in the country.

Durham, NC in the news

Top 25 U.S. Metros for Life Sciences: Boston, San Francisco & New York Lead the Way

The Durham metro area landed a close ninth behind Philadelphia among the best metros for life sciences in the U.S. The largest share of life sciences space in the Durham office market was the highest in the ranking.

The Best American Metros for Future-Proof Career Opportunities

Durham is home to ample employment opportunities in durable industries, such as life sciences, health care, and information technology, which contributed to the city's fifth-place finish in the ranking.

Durham, NC Office Spaces for Rent

American Underground - 324 Blackwell Street

Pine Ridge Office Centre

One RTP Tower

Locale321 - 321 East Chapel Hill Street

Bentley Ridge

Brassfield IV