1,601 Office Spaces for Rent in San Diego, CA

Find your best San Diego, CA office space among 1,601 for rent listings, which average an asking price of $41.6 per square foot.

Office Market FAQs

CA, San Diego - Via del Campo Ct
Regus
16868 Via Del Campo Court 1st & 2nd Floor, San Diego, CA
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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CA, San Diego - 770 First Avenue
Regus
770 1st Avenue #250, San Diego, CA
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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CA, Spaces Little Italy
Spaces
1420 Kettner Boulevard #100, 200 & 300, San Diego, CA
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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Fieldstone Plaza

5465 Morehouse Dr., Sorrento Valley, San Diego, CA
Property

Office

44,307 SF
Availability

1 Space

1,685 SF
Year Built

1986
For Lease Contact for pricing
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One Ten Plaza

110 West A Street, Core - Columbia, San Diego, CA
Property

Office

325,977 SF
Availability

18 Spaces

141,101 SF
Year Built

1971
For Lease Contact for pricing
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Innovation Corporate Center - 15333 Avenue of Science

15333 Avenue of Science, Carmel Mountain, San Diego, CA
Property

Office

78,880 SF
Availability

2 Spaces

45,058 SF
Year Built

2006
For Lease Contact for pricing
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Pacifica - North Site

5910 Pacific Center Blvd., Sorrento Valley, San Diego, CA
Property

Office

420,000 SF
Availability

1 Space

420,000 SF
Year Built

2027
For Lease Contact for pricing
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Centrewest

9710 Scranton Rd., Sorrento Valley, San Diego, CA
Property

Office

58,412 SF
Availability

2 Spaces

12,888 SF
Year Built

1990
For Lease

$39.00 - $45.00/SF/YR
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The Point - 16745 West Bernardo Drive

16745 West Bernardo Drive, Rancho Bernardo, San Diego, CA
Property

Office

93,699 SF
Availability

1 Space

5,718 SF
Year Built

1999
For Lease Contact for pricing
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Lomas Pacific I

9619 Chesapeake Dr., Kearny Mesa, San Diego, CA
Property

Office

44,599 SF
Availability

6 Spaces

16,374 SF
Year Built

1983
For Lease

$33.00/SF/YR
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Liberty Station - Building 27

2445 Truxtun Road, Midway, San Diego, CA
Property

Office

32,073 SF
Availability

1 Space

408 SF
Year Built

2008
For Lease

$3,000.00/MO
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Emerald Plaza

402 West Broadway, Core - Columbia, San Diego, CA
Property

Office

393,769 SF
Availability

22 Spaces

109,875 SF
Year Built

1991
For Lease

$32.40 - $36.00/SF/YR
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3911 Sorrento Valley Blvd.

3911 Sorrento Valley Blvd., Sorrento Valley, San Diego, CA
Property

Office

29,023 SF
Availability

1 Space

7,211 SF
Year Built

2015
For Lease Contact for pricing
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Park Terrace Health Center

17140 Bernardo Center Dr., Rancho Bernardo, San Diego, CA
Property

Office

82,157 SF
Availability

4 Spaces

16,721 SF
Year Built

1999
For Lease Contact for pricing
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Interstate Plaza II

2878 Camino Del Rio South, Mission Valley East, San Diego, CA
Property

Office

80,000 SF
Availability

4 Spaces

11,012 SF
Year Built

1989
For Lease Contact for pricing
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5050 Murphy Canyon Rd.

5050 Murphy Canyon Rd. , Kearny Mesa, San Diego, CA
Property

Office

28,741 SF
Availability

1 Space

5,908 SF
For Lease

$1.95/SF/MO
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The Elements at Wateridge

10221 Wateridge Circle, Sorrento Valley, San Diego, CA
Property

Office

277,071 SF
Availability

3 Spaces

59,122 SF
Year Built

1986
For Lease Contact for pricing
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Westridge

16644 West Bernardo Drive | San Diego, Rancho Bernardo, San Diego, CA
Property

Office
Availability

1 Space

6,145 SF
For Lease Contact for pricing
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Union Bank Building

3900 5th Avenue, Hillcrest, San Diego, CA
Property

Office

41,854 SF
Availability

3 Spaces

6,217 SF
Year Built

1989
For Lease

$2.65/SF/MO
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Coast 9

11080 Roselle Street, Torrey Pines Preserve, San Diego, CA
Property

Office

162,074 SF
Availability

1 Space

8,252 SF
Year Built

1975
For Lease Contact for pricing
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444 W C Street

444 W C Street, Core - Columbia, San Diego, CA
Property

Office

28,484 SF
Availability

1 Space

952 SF
For Lease

$1.95/SF/MO
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2448 Historic Decatur

2448 Historic Decatur, Midway, San Diego, CA
Property

Office
Availability

1 Space

4,459 SF
For Lease Contact for pricing
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3130 5th Ave

3130 5th Ave, Bankers Hill - Park West, San Diego, CA
Property

Office

3,800 SF
Availability

2 Spaces

504 SF
Year Built

1971
For Lease

$35.04 - $795.00/SF/YR
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Governor Executive Centre I

6165 Greenwich Drive, University City, San Diego, CA
Property

Office

52,915 SF
Availability

3 Spaces

11,491 SF
Year Built

1988
For Lease

$2.95/SF/MO
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Monarch Corporate Center - 9909 Mira Mesa Blvd

9909 Mira Mesa Blvd, Scripps Ranch, San Diego, CA
Property

Office

56,134 SF
Availability

1 Space

4,641 SF
Year Built

2002
For Lease Contact for pricing
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Waples Research Centre

9535 Waples Street, Sorrento Valley, San Diego, CA
Property

Office

50,055 SF
Availability

2 Spaces

28,103 SF
Year Built

1986
For Lease Contact for pricing
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The average rent for office space in San Diego is $41.6 per square foot. The minimum rental rate for office space in San Diego is $11.88 per square foot. Among listings of office space currently available for lease in San Diego, the maximum rental rate is $66 per square foot.

The most common factor that influences cost of office space in any location is the property class rating. For example, San Diego office space rated Class A asks an average of $46.25 per square foot. Class B office space in San Diego costs $36.44 per square foot, on average. Listings of office space in Class C buildings asked an average of $24.72 per square foot.

For more details on San Diego office space rent and sales prices, as well as overall market quality and new construction data, see San Diego Office Market Trends.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in San Diego, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 450,000 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in San Diego is 3,562 square feet, and the average office space size here is 8,902 square feet.

You can find 1,601 office listing(s) for lease in San Diego, which add up to a total of 15,080,943 square feet. Availability on the market includes a variety of office use types, such as General Office, Flex - Office, Medical Office, Creative Office, R&D - Office.

The most common office use type currently available for lease in San Diego is General Office, which is offered in 1,201 or 75.06% of listings. The second-most frequent office use type listed here is Flex - Office, which account for 99 or 6.19% of office space currently available. On the other end of the spectrum, the office use type least common among local listings is Flex - Industrial, which is available in 1 listing(s).

You can search 98 office sublease listing(s) in San Diego, which amount to a total of 1,548,603 square feet. Sublease opportunities on the market include General Office, R&D - Office, Medical Office. The San Diego neighborhood or submarket with the most sublease listings available is Sorrento Valley.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In San Diego, the greatest concentration of office space for lease opportunities is in Core - Columbia, Mission Valley East, Kearny Mesa.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The San Diego office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 44.91% of total office space listings in the city are in properties rated Class A. You will find the highest concentration of Class A office space in the Core - Columbia neighborhood of San Diego. Class B office space accounts for 41.29% of spaces listed on the leasing market. The neighborhood with the most Class B office space is Kearny Mesa. Class C office space makes up 3.75% of office space available in San Diego.

Buildings completed in and since the year 2000 account for 23.26% of office properties in the city and incorporate a total of 13,951,531 square feet. About 2.17% of office space in San Diego is in buildings that have been renovated at least once since 2000.

Out of the office space listings currently available in San Diego, you can find 345 LEED-certified or LEED-proposed option(s). A total of 47 building(s) here earned a LEED-certification — certification levelPlatinum (2), Gold (29), Silver (14). The local market includes 2 LEED-proposed office building(s) awaiting certification in San Diego.

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of San Diego? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

San Diego, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in San Diego: 106,862,261 Sq. Ft.

In 2024 the San Diego office market encompassed 106,862,261 square feet of space. Out of that total, 6,685,398 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 23,606,721 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 47.53% share of San Diego office inventory, while Class B office assets represent roughly 39.54% of the market total.

San Diego Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	23,606,721 Sq. Ft.	22.09%
100k to 500k Sq. Ft.	63,367,908 Sq. Ft.	59.3%
500k to 1M Sq. Ft.	6,685,398 Sq. Ft.	6.26%
> 1M Sq. Ft.	3,660,000 Sq. Ft.	3.42%

San Diego Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A+	995,425 Sq. Ft.	0.93%
Class A	50,786,362 Sq. Ft.	47.53%
Class B	42,251,366 Sq. Ft.	39.54%
Class C	1,717,902 Sq. Ft.	1.61%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

San Diego, CA Office Market Overview

San Diego, Calif., is the eighth-largest city in the U.S. and the second-largest in California, as well as part of the San Diego-Tijuana conurbation, which straddles the Mexican border. The city is famous for its sunny beaches, rich culture, vast U.S. Navy presence and talented workforce.

The main economic sectors in San Diego include military and defense, innovation, tourism, education and healthcare. Universities here — such as the University of California San Diego and San Diego State University — rank among the best in the nation for international business, and thousands of students here graduate with STEM degrees each year. San Diego is also one of the best cities in the country for Millennials to live and work.

With more and more businesses launching with the help of accelerators and incubators, demand for prime office in San Diego is strong. Nearly half of all San Diego office inventory is Class A.

Suburbs Home to 67% of All Offices Constructed in Last 20 Years

The very suburban markets of the Bay Area and San Diego added office space exactly there — in the suburbs. San Diego’s suburbs saw a whopping 91% of total office construction in the MSA — nearly 27 million square feet across 268 properties. Despite the fact that the dispersion of properties covered many of the outer regions of the San Diego market, the lion’s share of the properties were claimed by Carlsbad, Torrey Pines and the Sorrento Valley. That’s because San Diego’s biotechnology sector is largely concentrated in those submarkets — and they show no signs of slowing down. San Diego coworking has also been expanding recently.

Top 20 US Metros for Life Science Companies in 2022

12.3 million square feet of life sciences stock accounted for nearly 11% of the market — and the San Diego life sciences market is preparing for further growth: With 4.5 million square feet of new life sciences office projects in the pipeline, the San Diego metro area is looking at a market expansion of nearly 40% of its current stock.

Top Cities for Internet Connectivity & Speed

The biotech industry is prominent in San Diego, so WFH is definitely a possibility for its many residents. Notably, California as a state is actually 36th in the nation for speed. So, while many people are connected, the speeds aren’t quite up to par with the East Coast states

Flexible Workforce Demand Drives Growth of Coworking Sector

Notably, only two other markets saw their local listing rates grow by double digits during the same time frame: Listing rates for office space in San Diego and Boston increased 13.9% and 15.2% year-over-year, respectively.

2022’s Top 50 Most Expensive Office Sales

Further south, a portfolio sale of San Diego office spaces was just shy of the top 10 most expensive office transactions of 2022.

Office Pipeline 2023: Tight Race Between Manhattan & Boston for Top Spot

Block 2B — which ranked 16th among the largest projects in the U.S. office pipeline this year — will add some 765,000 square feet of new space to the San Diego market.

Artificial Intelligence in the U.S.: Top Innovators & Hottest Markets

San Diego was the last of the four California entries to rank among the 25 most innovative metros in the U.S., in no small part due to semiconductor and wireless communications technology manufacturer Qualcomm Technologies, Inc., which is headquartered here.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

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1,601 Office Spaces for Rent in San Diego, CA

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