Charleston, SC Commercial Real Estate for Lease and Sale
Explore 256 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
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850 Morrison Drive, Meeting St Manor - Cooper River Court, Charleston, SC
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King Street Ext, Radcliffeborough, Charleston, SCProperty Type
- Other
For Sale- $675,000
Built in 2008 / Property size 800 SF -
394 Meeting St, East Side Charleston, Charleston, SCSpace Type
- Office
For Lease- $20.00/SF/YR
2 spaces available / 1,122 - 3,039 SF -
174 Meeting Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $45.00/SF/YR
1 space available / 14,502 SF -

What type of listing property are you looking for?
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1031 Legrand Blvd, Daniel Island, Charleston, SCSpace Type
- Industrial
For Lease- $5.95/SF/YR
1 space available / 108,405 SF -
1460 Tobias Gadson Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Office
For Lease- $26.00/SF/YR
1 space available / 9,139 SF -
40 Line St, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Retail
For Lease- $35.00 - $55.00/SF/YR
4 spaces available / 930 - 8,479 SF -
1640 Meeting Street, Four Mile Hibernian, North Charleston, SC
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645 E Bay St, East Side Charleston, Charleston, SCProperty Type
- VacantLand
For Sale- $1,395,000
Built in 1880 / Property size 3,018 SF -
284 Meeting St, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $65.00/SF/YR
1 space available / 1,600 SF -
Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type- Land
For Lease- $19,000.00/YR
1 space available / 40,075.2 SF -
200 Meeting St, Downtown Charleston, Charleston, SC
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1042 Legrand Boulevard Unit A, Daniel Island, Wando, SCSpace Type
- Industrial
For Lease- $18.00/SF/YR
1 space available / 9,250 SF -
677 King Street, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Retail
For Lease- $60.00/SF/YR
1 space available / 1,920 SF -
12 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type
- Office
For Lease- $16.00/SF/YR
1 space available / 1,954 SF -
630 Skylark Drive, Dupont Area - Orleans, Charleston, SCSpace Type
- Retail
For Lease- $22.00/SF/YR
1 space available / 1,040 SF -
1219 Hobart Avenue, Maryville - Asleyville, Charleston, SCSpace Type
- Office
For Lease- $20.00/SF/YR
1 space available / 2,567 SF -
247 Rutledge Ave, Medical University of SC, Charleston, SCProperty Type
- Multi-Family
For Sale- $1,249,000
Built in 2014 / Property size 2,676 SF -
1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SCSpace Type
- Industrial
For Lease- $9.50/SF/YR
1 space available / 23,537 SF -
115 Fairchild Street Suite 100, Charleston, SCSpace Type
- Private Offices
For Lease-
From $414/month
Space for 1 to 15 people -
2201 Mechanic St, Silver Hill - Magnolia, Charleston, SCSpace Type
- Flex Space
For Lease- $16.00/SF/YR
1 space available / 7,000 SF -
2585 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type
- Land
For Lease- $8,500.00/MO
1 space available / 65,775.6 SF -
701 E Bay St, East Side Charleston, Charleston, SC
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720 Magnolia Road, Carolina Terrace - Magnolia, Charleston, SCSpace Type
- Other
For Lease- $2,495.00/MO
1 space available / 1,315 SF -
1859 Summerville Ave ste 800, Charleston, SCSpace Type
- Desks
For Lease-
From $45/day
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62 Brigade St, Silver Hill - Magnolia, Charleston, SCSpace Type
- Industrial
For Lease- $18.00/SF/YR
1 space available / 1,600 SF -
2387 Clements Ferry Road, Daniel Island, Charleston, SCSpace Type
- Office
For Lease- $26.95/SF/YR
1 space available / 33,492 SF -
517 King Street, #4, Cannonborough - Elliottborough, Charleston, SCSpace Type- Retail
For Lease- $30.00/SF/YR
1 space available / 4,334 SF -
2457 Ashley River Rd, Pierpont, Charleston, SC -
140 Spring Street, Medical University of SC, Charleston, SCProperty Type
- Other
For Sale- $2,995,000
Property size 3,028 SF -
1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SCSpace Type
- Office
For Lease- $4,500.00/MO
1 space available / 2,702 SF -
63 Montagu St, Harleston Village, Charleston, SCProperty Type
- Multi-Family
For Sale- $1,299,000
Built in 1922 / Property size 1,546 SF -
806 Elsey Dr, Dupont Area - Orleans, Charleston, SCSpace Type
- Industrial
For Lease- $17.00/SF/YR
1 space available / 2,500 SF -
125 Fairchild Street, Daniel Island, Charleston, SCSpace Type
- Office
For Lease- $24.00 - $28.00/SF/YR
2 spaces available / 8,500 - 26,000 SF -
1940 Algonquin Road, Silver Hill - Magnolia, Charleston, SCSpace Type
- Office
For Lease- $30.00/SF/YR
14 spaces available / 1,523 - 22,000 SF -
2563 Clements Ferry Rd, Daniel Island, Charleston, SC
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2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC
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3937 Savannah Hwy, Marsh View, Johns Island, SCSpace Type
- Office
For Lease- $7,000.00/MO
1 space available / 942 SF -
460 King Street Suite 200, Charleston, SCSpace Type- Private Offices
For Lease-
From $1,425/month
Space for up to 2 people -
40 Calhoun Street, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Office
For Lease- $39.00 - $468.00/SF/YR
5 spaces available / 1,356 - 5,153 SF -
284 Meeting St, Downtown Charleston, Charleston, SCProperty Type
- Office
For Sale- $1,650,000
Built in 2026 / Property size 1,600 SF -
Clements Ferry Rd, Daniel Island, Charleston, SCProperty Type- VacantLand
For Sale- $170,000
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177 Meeting Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $45.00/SF/YR
5 spaces available / 2,828 - 6,425 SF -
1795 King Street Ext, Silver Hill - Magnolia, Charleston, SCProperty Type
- Industrial
For Sale- $3,900,000
Property size 20,000 SF -
2000 Sam Rittenberg Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Retail
For Lease- $25.00 - $32.00/SF/YR
4 spaces available / 1,100 - 2,315 SF -
11 Isabella St Suite A, East Central Charleston, Charleston, SCSpace Type
- Office
For Lease- $29.00/SF/YR
1 space available / 1,650 SF -
20 Cypress St, East Central Charleston, Charleston, SCProperty Type- Land
For Sale- $359,000
Property size 0.06 Acre -
158 Church Street 2nd-3rd Floor, Charleston, SCSpace Type
- Private Offices
For Lease-
From $1,500/month
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497 Jessen Lane, Daniel Island, Wando, SCSpace Type
- Industrial
For Lease- $18.00/SF/YR
1 space available / 8,062 SF -
61 Broad St, South of Broad, Charleston, SCProperty Type
- Office
For Sale- $2,700,000
Built in 1815 / Property size 7,058 SF -
1505 King Street, Silver Hill - Magnolia, Charleston, SC
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889 Folly Rd, Centerville - Camp Road Estates, Charleston, SCProperty Type- Other
For Sale- $1,550,000
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198 Rutledge Avenue, Cannonborough - Elliottborough, Charleston, SCProperty Type
- Office
For Sale- $1,740,000
Property size 3,243 SF