Charleston, SC Commercial Real Estate for Lease and Sale
Explore 250 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
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1940 Algonquin Road, Silver Hill - Magnolia, Charleston, SCSpace Type- Office
For Lease- $30.00/SF/YR
14 spaces available / 1,523 - 22,000 SF -
497 Jessen Lane, Daniel Island, Wando, SCSpace Type- Industrial
For Lease- $18.00/SF/YR
1 space available / 8,062 SF -
200 Meeting St, Downtown Charleston, Charleston, SC -
2333 Ashley River Road, Pierpont, Charleston, SCProperty Type- Other
For Sale- $6,500,000
Built in 1999 / Property size 55,602 SF -

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172 Ashley Avenue, Medical University of SC, Charleston, SCSpace Type- Office
For Lease- $37.50/SF/YR
1 space available / 1,978 SF -
701 E Bay St, East Side Charleston, Charleston, SC -
100 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $43.00/SF/YR
1 space available / 9,675 SF -
1045 5th Ave, Maryville - Asleyville, Charleston, SCSpace Type- Industrial
For Lease- $21.00/SF/YR
1 space available / 4,200 SF -
284 Meeting St, Downtown Charleston, Charleston, SCProperty Type- Office
For Sale- $1,650,000
Built in 2026 / Property size 1,600 SF -
2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC -
170 Meeting Street Suite 200, Charleston, SCSpace Type- Private Offices
For Lease-
From $424/month
Space for 1 to 50 people -
1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SCSpace Type- Industrial
For Lease- $9.50/SF/YR
1 space available / 23,537 SF -
806 Elsey Dr, Dupont Area - Orleans, Charleston, SCSpace Type- Industrial
For Lease- $17.00/SF/YR
1 space available / 2,500 SF -
83 Mary St, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $35.00/SF/YR
3 spaces available / 1,246 - 1,542 SF -
1859 Summerville Avenue, Rosemont, North Charleston, SC -
889 Folly Rd, Centerville - Camp Road Estates, Charleston, SCProperty Type- Other
For Sale- $1,550,000
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1980 Technology Drive, Daniel Island, Charleston, SC -
177 Meeting Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $45.00/SF/YR
5 spaces available / 2,828 - 6,425 SF -
2387 Clements Ferry Road, Daniel Island, Charleston, SCSpace Type- Office
For Lease- $26.95/SF/YR
1 space available / 33,492 SF -
2414 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 1,010 SF -
11 Isabella St Suite A, East Central Charleston, Charleston, SCSpace Type- Office
For Lease- $29.00/SF/YR
1 space available / 1,650 SF -
2525 Savannah Hwy, Cherokee Hall - Sylvan Shores, Charleston, SCProperty Type- Other
For Sale- $595,000
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1042 Legrand Boulevard Unit A, Daniel Island, Wando, SCSpace Type- Industrial
For Lease- $18.00/SF/YR
1 space available / 9,250 SF -
125 Fairchild Street, Daniel Island, Charleston, SCSpace Type- Office
For Lease- $24.00 - $28.00/SF/YR
2 spaces available / 8,500 - 26,000 SF -
215 Benefitfocus Way, Daniel Island, SC -
18 Broad Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $1,295.00 - $4,500.00/MO
5 spaces available / 235 - 1,000 SF -
1460 Tobias Gadson Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type- Office
For Lease- $26.00/SF/YR
1 space available / 9,139 SF -
2125 Charlie Hall Blvd, Essex Farms - Carolina Bay, Charleston, SCSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 13,113 SF -
123 Sportsman Island Drive, Daniel Island, Charleston, SCProperty Type- VacantLand
For Sale- $800,000
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1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SCProperty Type- Office
For Sale- $950,000
Property size 2,702 SF -
63 Montagu St, Harleston Village, Charleston, SCProperty Type- Multi-Family
For Sale- $3,099,000
Built in 1922 / Property size 3,092 SF -
2090 Executive Hall Rd, Savage Road - Citadel Mall, Charleston, SCSpace Type- Office
For Lease- $18.00/SF/YR
1 space available / 850 SF -
174 Meeting Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $45.00/SF/YR
1 space available / 14,502 SF -
2270 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SCSpace Type- Office
For Lease- $32.00/SF/YR
1 space available / 3,746 SF -
40 Line St, Cannonborough - Elliottborough, Charleston, SCSpace Type- Retail
For Lease- $35.00 - $55.00/SF/YR
4 spaces available / 930 - 8,479 SF -
200 Spring St, Gadsden Green, Charleston, SC -
2814 Clements Ferry Rd, Daniel Island, Charleston, SCProperty Type- VacantLand
For Sale- $1,200,000
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420 Brandam Lane, Daniel Island, Charleston, SCSpace Type- Industrial
For Lease- $22.00 - $23.00/SF/YR
3 spaces available / 1,800 - 3,600 SF -
12 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type- Office
For Lease- $16.00/SF/YR
1 space available / 1,954 SF -
20 Cypress St, East Central Charleston, Charleston, SCProperty Type- Land
For Sale- $359,000
Property size 0.06 Acre -
1301 Charleston Regional Pkwy, Daniel Island, Charleston, SC -
1501 Secessionville Road, Seaside Plantation - Wexford Sound, Charleston, SC -
King Street Ext, Radcliffeborough, Charleston, SCProperty Type- Other
For Sale- $675,000
Built in 2008 / Property size 800 SF -
63 Montagu St, Harleston Village, Charleston, SCProperty Type- Multi-Family
For Sale- $1,299,000
Built in 1922 / Property size 1,546 SF -
2457 Ashley River Rd, Pierpont, Charleston, SC -
2201 Mechanic St, Silver Hill - Magnolia, Charleston, SCSpace Type- Flex Space
For Lease- $16.00/SF/YR
1 space available / 7,000 SF -
1219 Hobart Avenue, Maryville - Asleyville, Charleston, SCProperty Type- Office
For Sale- $990,000
Property size 2,600 SF -
247 Rutledge Ave, Medical University of SC, Charleston, SCProperty Type- Multi-Family
For Sale- $1,249,000
Built in 2014 / Property size 2,676 SF -
61 Broad St, South of Broad, Charleston, SCProperty Type- Office
For Sale- $2,700,000
Built in 1815 / Property size 7,058 SF -
1587 Savannah Hwy, Indigo Point - Harrison, Charleston, SCSpace Type- Office
For Lease- $21.00/SF/YR
1 space available / 2,165 SF -
194 Seven Farms Drive, Daniel Island, Charleston, SC -
Whippoorwill Farm Rd, Harbor Woods - Bayview Farms, Johns Island, SC -
1064 Gardner Road, Dupont Area - Orleans, Charleston, SCSpace Type- Office
For Lease- $26.00/SF/YR
3 spaces available / 962 - 2,652 SF