Charleston, SC Commercial Real Estate for Lease and Sale
Explore 197 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
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142 Spring St, Medical University of SC, Charleston, SCProperty Type- Other
For Sale- $2,995,000
Built in 1890 / Property size 2,550 SF -
1301 Charleston Regional Pkwy, Daniel Island, Charleston, SC -
125 Fairchild Street 2nd Floor, Charleston, SCSpace Type- Private Offices
For Lease-
From $539/month
Space for 1 to 15 people -
170 Meeting Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $42.00/SF/YR
1 space available / 6,187 SF -

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62 Brigade St, Silver Hill - Magnolia, Charleston, SCSpace Type- Industrial
For Lease- $18.00/SF/YR
1 space available / 1,600 SF -
1 South Park Circle, Savage Road - Citadel Mall, Charleston, SCSpace Type- Office
For Lease- $24.00/SF/YR
2 spaces available / 3,843 - 9,275 SF -
1640 Meeting Street, Four Mile Hibernian, North Charleston, SC -
145 King Street, Harleston Village, Charleston, SCSpace Type- Office
For Lease- $34.00 - $36.00/SF/YR
6 spaces available / 1,204 - 6,191 SF -
192 E Bay St Ste 205, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $2,500.00/MO
1 space available / 420 SF -
40 Calhoun Street, Cannonborough - Elliottborough, Charleston, SCSpace Type- Office
For Lease- $38.00 - $456.00/SF/YR
5 spaces available / 1,073 - 5,153 SF -
677 King Street, Cannonborough - Elliottborough, Charleston, SCSpace Type- Retail
For Lease- $60.00/SF/YR
1 space available / 1,920 SF -
2333 Ashley River Road, Pierpont, Charleston, SCProperty Type- Other
For Sale- $6,500,000
Built in 1999 / Property size 55,602 SF -
901 Savannah Hwy, Bymes Downs - Coburg, Charleston, SC -
92 Folly Road Boulevard, Wappoo Heights - Windermere, Charleston, SCSpace Type- Retail
For Lease- $30.00 - $50.00/SF/YR
3 spaces available / 1,504 - 2,205 SF -
125 Wappoo Creek Drive, Wappoo Creek - McLeod Plantation, Charleston, SCSpace Type- Office
For Lease- $23.00/SF/YR
1 space available / 2,200 SF -
1859 Summerville Avenue, Rosemont, North Charleston, SC -
158 Church Street 2nd-3rd Floor, Charleston, SCCity House - 158 Church St
City HouseSpace Type- Private Offices
For Lease-
From $1,500/month
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1795 King Street Ext, Silver Hill - Magnolia, Charleston, SCProperty Type- Industrial
For Sale- $3,900,000
Property size 20,000 SF -
115 Fairchild Street, Daniel Island, SCSpace Type- Office
For Lease- $29.95 - $32.00/SF/YR
6 spaces available / 2,157 - 8,762 SF -
51 Markfield Dr, Indigo Point - Harrison, Charleston, SCProperty Type- Other
For Sale- $765,000
Built in 1987 / Property size 2,155 SF -
2563 Clements Ferry Rd, Daniel Island, Charleston, SC -
1445 Greenleaf Road, Silver Hill - Magnolia, Charleston, SCSpace Type- Industrial
For Lease- $9.50/SF/YR
1 space available / 23,537 SF -
720 Magnolia Road, Carolina Terrace - Magnolia, Charleston, SCSpace Type- Office
For Lease- $2,495.00/MO
1 space available / 850 SF -
115 Central Island St, Daniel Island, Charleston, SC -
1859 Summerville Ave ste 800, Charleston, SCLocal Works - 1859 Summerville Avenue
Local WorksSpace Type- Desks
For Lease-
From $45/day
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537 Folly Road, Laurel Park - Marlborough, Charleston, SCSpace Type- Office
For Lease- $20.66/SF/YR
1 space available / 2,087 SF -
1940 Algonquin Road, Silver Hill - Magnolia, Charleston, SCSpace Type- Office
For Lease- $30.00/SF/YR
14 spaces available / 1,523 - 22,000 SF -
415 Jessen Ln, Daniel Island, Wando, SC -
King Street Ext, Silver Hill - Magnolia, Charleston, SCProperty Type- Other
For Sale- $675,000
Built in 2008 / Property size 800 SF -
2000 Sam Rittenberg Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type- Retail
For Lease- $25.00 - $32.00/SF/YR
4 spaces available / 1,100 - 2,315 SF -
701 East Bay Street, East Side Charleston, Charleston, SC -
215 Benefitfocus Way, Daniel Island, SC -
177 Meeting Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $42.00/SF/YR
6 spaces available / 2,582 - 5,490 SF -
20 Cypress St, East Central Charleston, Charleston, SCProperty Type- Land
For Sale- $359,000
Property size 0.06 Acre -
61 Broad St, South of Broad, Charleston, SCProperty Type- Office
For Sale- $2,700,000
Built in 1815 / Property size 7,058 SF -
40 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $1,100.00 - $1,450.00/MO
5 spaces available / 314 - 432 SF -
100 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type- Office
For Lease- $43.00/SF/YR
1 space available / 9,675 SF -
192 East Bay Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $25.00 - $38.51/SF/YR
2 spaces available / 148 - 693 SF -
234 Seven Farms Drive, Daniel Island, SCSpace Type- Office
For Lease- $60.77 - $1,450.00/SF/YR
3 spaces available / 255 - 311 SF -
2270 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SCSpace Type- Office
For Lease- $32.00/SF/YR
1 space available / 3,746 SF -
2201 Mechanic St, Silver Hill - Magnolia, Charleston, SCSpace Type- Flex Space
For Lease- $16.00/SF/YR
1 space available / 7,000 SF -
2387 Clements Ferry Road, Daniel Island, Charleston, SCSpace Type- Office
For Lease- $26.95/SF/YR
1 space available / 33,492 SF -
460 King Street Suite 200, Charleston, SCOffice Evolution - Charleston
Office EvolutionSpace Type- Private Offices
For Lease-
From $1,425/month
Space for up to 2 people -
174 Meeting Street, Downtown Charleston, Charleston, SCSpace Type- Office
For Lease- $42.00/SF/YR
1 space available / 14,502 SF -
1980 Technology Drive, Daniel Island, Charleston, SC -
179 Church Street, Downtown Charleston, Charleston, SCSpace Type- Retail
For Lease- $87.55/SF/YR
1 space available / 1,105 SF -
2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC -
420 Meeting St, East Side Charleston, Charleston, SCProperty Type- Other
For Sale- $5,000,000
Built in 1992 / Property size 1,270 SF -
140 Spring Street, Medical University of SC, Charleston, SCProperty Type- Other
For Sale- $3,100,000
Property size 3,028 SF -
630 Skylark Drive, Dupont Area - Orleans, Charleston, SCSpace Type- Retail
For Lease- $22.00/SF/YR
1 space available / 1,040 SF -
1668 Sam Rittenberg Blvd, Northbridge Terrace - Parkshore, Charleston, SCSpace Type- Retail
For Lease- $17.00 - $18.00/SF/YR
2 spaces available / 2,280 - 2,500 SF -
2467 Savannah Hwy, Cherokee Hall - Sylvan Shores, Charleston, SC -
40 Line St, Cannonborough - Elliottborough, Charleston, SCSpace Type- Retail
For Lease- $35.00 - $55.00/SF/YR
4 spaces available / 930 - 8,479 SF