Charleston, SC Commercial Real Estate for Lease and Sale
Explore 254 listing(s) of commercial real estate in Charleston, SC to find the best space for your business.
-
18 Broad Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $1,295.00 - $4,500.00/MO
5 spaces available / 235 - 1,000 SF -
1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SCSpace Type
- Office
For Lease- $4,500.00/MO
1 space available / 2,702 SF -
2467 Savannah Hwy, Cherokee Hall - Sylvan Shores, Charleston, SC
-
2000 Sam Rittenberg Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Retail
For Lease- $25.00 - $32.00/SF/YR
4 spaces available / 1,100 - 2,315 SF -

What type of listing property are you looking for?
-
2201 Mechanic St, Silver Hill - Magnolia, Charleston, SCSpace Type
- Flex Space
For Lease- $16.00/SF/YR
1 space available / 7,000 SF -
20 Cypress St, East Central Charleston, Charleston, SCProperty Type- Land
For Sale- $359,000
Property size 0.06 Acre -
158 Church Street 2nd-3rd Floor, Charleston, SCSpace Type
- Private Offices
For Lease-
From $1,500/month
-
630 Skylark Drive, Dupont Area - Orleans, Charleston, SCSpace Type
- Retail
For Lease- $22.00/SF/YR
1 space available / 1,040 SF -
1795 King Street Ext, Silver Hill - Magnolia, Charleston, SCProperty Type
- Industrial
For Sale- $3,900,000
Property size 20,000 SF -
460 King Street Suite 200, Charleston, SCSpace Type- Private Offices
For Lease-
From $1,425/month
Space for up to 2 people -
2270 Ashley Crossing Drive, Drayton Quarters - Magwood, Charleston, SCSpace Type
- Office
For Lease- $32.00/SF/YR
1 space available / 3,746 SF -
720 Magnolia Road, Carolina Terrace - Magnolia, Charleston, SCSpace Type
- Retail
For Lease- $2,495.00/MO
1 space available / 1,315 SF -
2414 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 1,010 SF -
40 Calhoun Street, Mazyck - Wraggborough, Charleston, SCSpace Type
- Office
For Lease- $1,100.00 - $1,450.00/MO
6 spaces available / 314 - 512 SF -
284 Meeting St, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $65.00/SF/YR
1 space available / 1,600 SF -
170 Meeting Street Suite 200, Charleston, SCSpace Type
- Private Offices
For Lease-
From $424/month
Space for 1 to 50 people -
2585 Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type
- Land
For Lease- $8,500.00/MO
1 space available / 65,775.6 SF -
2090 Executive Hall Rd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Office
For Lease- $18.00/SF/YR
1 space available / 850 SF -
1483 Tobias Gadson Blvd, Savage Road - Citadel Mall, Charleston, SC
-
200 Meeting St, Downtown Charleston, Charleston, SC
-
2310 Charleston Regional Pkwy, Daniel Island, Charleston, SC
-
40 Calhoun Street, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Office
For Lease- $39.00 - $468.00/SF/YR
5 spaces available / 1,356 - 5,153 SF -
2814 Clements Ferry Rd, Daniel Island, Charleston, SCProperty Type
- VacantLand
For Sale- $1,200,000
-
12 Farmfield Ave, Parkwood - Farmfield, Charleston, SCSpace Type
- Office
For Lease- $16.00/SF/YR
1 space available / 1,954 SF -
115 Fairchild Street, Daniel Island, SCSpace Type
- Office
For Lease- $29.95 - $32.00/SF/YR
5 spaces available / 2,157 - 8,762 SF -
1587 Savannah Hwy, Indigo Point - Harrison, Charleston, SCSpace Type
- Office
For Lease- $20.00/SF/YR
1 space available / 2,165 SF -
1859 Summerville Avenue, Rosemont, North Charleston, SC
-
420 Brandam Lane, Daniel Island, Charleston, SCSpace Type
- Industrial
For Lease- $22.00 - $23.00/SF/YR
3 spaces available / 1,800 - 3,600 SF -
517 King Street, #4, Cannonborough - Elliottborough, Charleston, SCSpace Type- Retail
For Lease- $30.00/SF/YR
1 space available / 4,334 SF -
Clements Ferry Rd, Daniel Island, Charleston, SCSpace Type- Land
For Lease- $19,000.00/YR
1 space available / 40,075.2 SF -
140 Spring Street, Medical University of SC, Charleston, SCProperty Type
- Other
For Sale- $2,995,000
Property size 3,028 SF -
215 Benefitfocus Way, Daniel Island, SC
-
125 Fairchild Street, Daniel Island, Charleston, SCSpace Type
- Office
For Lease- $24.00 - $28.00/SF/YR
2 spaces available / 8,500 - 26,000 SF -
Cannon St & Rutledge Ave, Cannonborough - Elliottborough, Charleston, SCProperty Type
- VacantLand
For Sale- $9,850,000
-
46 State St, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $36.00/SF/YR
1 space available / 1,500 SF -
172 Ashley Avenue, Medical University of SC, Charleston, SCSpace Type
- Office
For Lease- $37.50/SF/YR
1 space available / 1,978 SF -
63 Montagu St, Harleston Village, Charleston, SCProperty Type
- Multi-Family
For Sale- $3,099,000
Built in 1922 / Property size 3,092 SF -
Whippoorwill Farm Rd, Harbor Woods - Bayview Farms, Johns Island, SC
-
517 King Street, #4, Cannonborough - Elliottborough, Charleston, SCProperty Type- Retail
For Sale- $2,383,700
Property size 4,334 SF -
1460 Tobias Gadson Blvd, Savage Road - Citadel Mall, Charleston, SCSpace Type
- Office
For Lease- $26.00/SF/YR
1 space available / 9,139 SF -
83 Mary St, Mazyck - Wraggborough, Charleston, SCSpace Type
- Office
For Lease- $35.00/SF/YR
3 spaces available / 1,246 - 1,542 SF -
850 Morrison Drive, Meeting St Manor - Cooper River Court, Charleston, SC
-
62 Brigade St, Silver Hill - Magnolia, Charleston, SCSpace Type
- Industrial
For Lease- $18.00/SF/YR
1 space available / 1,600 SF -
284 Meeting St, Downtown Charleston, Charleston, SCProperty Type
- Office
For Sale- $1,650,000
Built in 2026 / Property size 1,600 SF -
1064 Gardner Road, Dupont Area - Orleans, Charleston, SCSpace Type
- Office
For Lease- $26.00/SF/YR
3 spaces available / 962 - 2,652 SF -
1524 Ashley River Rd, Village Square - Pinecrest Gardens, Charleston, SCProperty Type
- Office
For Sale- $950,000
Property size 2,702 SF -
174 Meeting St, Downtown Charleston, Charleston, SC
-
170 Meeting Street, Downtown Charleston, Charleston, SCSpace Type
- Office
For Lease- $42.00 - $45.00/SF/YR
2 spaces available / 4,310 - 6,187 SF -
1640 Meeting Street, Four Mile Hibernian, North Charleston, SC
-
1219 Hobart Avenue, Maryville - Asleyville, Charleston, SCSpace Type
- Office
For Lease- $20.00/SF/YR
1 space available / 2,567 SF -
677 King Street, Cannonborough - Elliottborough, Charleston, SCSpace Type
- Retail
For Lease- $60.00/SF/YR
1 space available / 1,920 SF -
2457 Ashley River Rd, Pierpont, Charleston, SC -
123 Sportsman Island Drive, Daniel Island, Charleston, SCProperty Type
- VacantLand
For Sale- $800,000