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South San Francisco Office Rent Price & Sales Report

2024 Office Space Rent & Sales

  • $86.62 2024 Avg. Asking Rent
  • 26.90% 2024 Office Vacancy Rate

South San Francisco office price per square foot in 2024 was $86.62 on average. The local office market recorded an average vacancy rate of 26.90% across all asset classes combined.

See how this market compares to the national average: U.S. office space rent & sales.

Average Rent by Office Class

2024 Average Office Rent per Square Foot

  • California Class A & A+ Office Space$60.31
  • California Class B Office Space$38.42
  • California Class C Office Space$26.20

South San Francisco, CA Office Asking Rents by Class

Office Spaces for Rent in California

  • Fresno Office Space
  • Visalia Office Space
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Coworking Spaces in California

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2024 Office Construction in South San Francisco, CA

  • South San Francisco, CA Total SF completed in 2024 1,198,000
  • South San Francisco, CA Total SF under construction in 2025 326,000

During 2024, 1,198,000 square feet of new office space were delivered across the market. At the close of 2024, the South San Francisco office inventory included 5 buildings equal to or larger than 25,000 square feet, which comprised 1,198,000 square feet of office space. Looking forward, development activity throughout 2025 is estimated to add 326,000 square feet of office space to the market, before year-end.

Largest Office Properties Recently Completed in South San Francisco
Office building Address SF Completed
Kilroy Oyster Point - Phase II 389 Oyster Point Blvd, 94080 865,000 2025
Southline - Building 1 30 Tanforan Avenue, 94080 375,000 2024
Vantage - Building B 494 Forbes Blvd, 94080 188,000 2024
Gateway of Pacific V - North Building 475 Eccles Avenue, 94080 160,000 2024
Gateway of Pacific V - South Building 485 Eccles Avenue, 94080 160,000 2024
The Nexus on Grand 233 East Grand Avenue, 94080 148,500 2023
201 Haskins Way 201 Haskins Way, 94080 311,368 2021
The Cove at Oyster Point VII 131 Oyster Point Blvd, 94080 175,830 2019
Genesis - North Tower 2 Tower Place, 94080 381,523 2018
161 El Camino Real 161 El Camino Real, 94080 3,010 2017

Worth noting among recent office completions on the South San Francisco market is Kilroy Oyster Point - Phase II, which is currently the largest new office development in the city, at 865,000 square feet.

Data provided by Commercial Edge

See reports for other markets

  • Los Angeles Office Rent Price
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  • Beverly Hills Office Rent Price

This market stats report is based on analysis of city-level data that includes office properties equal to or larger than 25,000 square feet in size. Averages were calculated based on values dated January 1st 2024 through December 31st 2024. Construction pipeline data represented herein is valid as of February 2025. The information on this page was compiled using data provided by CommercialEdge, a market intelligence solution which offers comprehensive real market knowledge on all South San Francisco commercial properties sized 25,000 square feet or larger.

While every effort was made to ensure the accuracy of the data presented in this report, the information is provided “as is” and neither CommercialCafe nor CommercialEdge can guarantee that the information provided is complete.


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