51 Office Spaces for Rent in Saint Charles, MO

Find the best Saint Charles, MO office space among 51 for rent listings currently on the market.

SSM Health Medical Buildings 1 & 2

330 1st Capitol Drive, St. Charles, MO
Property

Office

81,400 SF
Availability

9 Spaces

15,188 SF
Year Built

1987
For Lease

$24.50 - $28.00/SF/YR
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Streets of St. Charles - 1450 Beale Street

1450 Beale Street, St. Charles, MO
Property

Office

60,000 SF
Availability

1 Space

4,768 SF
Year Built

2018
For Lease

$33.00/SF/YR
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3817-3841 Millstone Parkway

3817-3841 Millstone Parkway, Saint Charles, MO
Property

Industrial

130,000 SF
Availability

1 Space

86,800 SF
For Lease

$5.95 - $6.75/SF/YR
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1000 Technology Drive

1000 Technology Drive, Weldon Spring, O'Fallon, MO
Property

Office

518,601 SF
Availability

2 Spaces

126,000 SF
Year Built

2002
For Lease Contact for pricing
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Streets of St. Charles - 1520 South 5th Street

1520 South 5th Street, St. Charles, MO
Property

Office

100,633 SF
Availability

6 Spaces

11,728 SF
Year Built

2011
For Lease

$28.00 - $29.00/SF/YR
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Streets of St. Charles

1450 Beale St., Saint Charles, MO
Property

Office

36,419 SF
Availability

2 Spaces

36,419 SF
Year Built

2019
For Lease Contact for pricing
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Three Flags Business Center

1360 South 5th Street, St. Charles, MO
Property

Office

61,754 SF
Availability

7 Spaces

5,831 SF
Year Built

1972
For Lease Contact for pricing
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1600 Heritage Landing

1600 Heritage Landing, St. Charles, MO
Property

Office

62,898 SF
Availability

8 Spaces

16,316 SF
Year Built

1980
For Lease

$14.00 - $16.00/SF/YR
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The Commons
The Commons
3324 Rue Royale Street, Saint Charles, MO
Services

Virtual Office

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Catering

Complimentary coffee & tea

Free water

High-speed wifi

Parking

Printer

Privacy booths

Projector

Receptionist/Secretarial services

TV/Monitor
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2085 Collier Corporate Pkwy

2085 Collier Corporate Pkwy, Saint Charles, MO
Property

Office

2,000 SF
Availability

1 Space

2,000 SF
Year Built

1995
For Lease

$18.00/SF/YR
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5377 Highway N
Cottleville Synergy Center
5377 Highway N, Saint Charles, MO
Services

Virtual Office

Event Space

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Free water

High-speed wifi

Mail services

Parking

Receptionist/Secretarial services

Utilities included
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2722 South Saint Peters Parkway
The Heritage Small Business Hub
2722 South Saint Peters Parkway, St. Peters, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Free water

High-speed wifi

Receptionist/Secretarial services

TV/Monitor

White boards
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119 South Main Street
OPO Startups
119 South Main Street, Saint Charles, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Catering

Cleaning services

Complimentary coffee & tea

High-speed internet

High-speed wifi

Office furniture

Parking

Podcast room

Snacks

TV/Monitor
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2300 Highway 94 South Outer Rd

2300 Highway 94 South Outer Rd, Saint Charles, MO
Property

Office

15,000 SF
Availability

2 Spaces

5,750 SF
Year Built

1998
For Lease

$14.95 - $15.95/SF/YR
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The Streets of St Charles

1650 Beale Street, Saint Charles, MO
Property

Office

1,606 SF
Availability

1 Space

1,606 SF
For Lease

$22.00/SF/YR
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4071 North Saint Peters Parkway

4071 North Saint Peters Parkway, St. Peters, MO
Property

Retail

5,863 SF
Availability

2 Spaces

4,894 SF
For Lease

$10.78 - $13.00/SF/YR
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416 S Main Street

416 S Main St, Saint Charles, MO
Property

Retail

4,161 SF
Availability

1 Space

1,225 SF
Year Built

1870
For Lease

$21.00 - $25.00/SF/YR
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1540 Country Club Plaza Dr

1540 Country Club Plaza Dr, Saint Charles, MO
Property

Office

20,924 SF
Availability

1 Space

12,634 SF
Year Built

1985
For Lease

$13.00/SF/YR
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Campus Plaza

2040 Campus Dr, Saint Charles, MO
Property

Mixed Use

6,680 SF
Availability

1 Space

800 SF
Year Built

1975
For Lease

$12.00/SF/YR
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3010 North Highway 94

3010 North Highway 94, Saint Charles, MO
Property

Retail

40,200 SF
Availability

3 Spaces

6,485 SF
For Lease

$12.00/SF/YR
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1120 Wolfrum Rd

1120 Wolfrum Rd, Saint Charles, MO
Property

Office

16,800 SF
Availability

2 Spaces

5,472 SF
Year Built

2004
For Lease

$16.00 - $19.00/SF/YR
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1 Point West Blvd

1 Point West Blvd, Saint Charles, MO
Property

Office

3,060 SF
Availability

1 Space

3,060 SF
Year Built

2005
For Lease

$16.00/SF/YR
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6020 Weldon Spring Parkway

6020 Weldon Spring Parkway, Weldon Spring, MO
Property

Office

8,562 SF
Availability

2 Spaces

3,710 SF
For Lease

$14.95 - $15.95/SF/YR
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Executive Centre I

5600 Mexico Rd, City Center Park, St. Peters, MO
Property

Office
Availability

1 Space

2,750 SF
Year Built

1996
For Lease Contact for pricing
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2046 Queens Brooke Boulevard

2046 Queens Brooke Boulevard, St. Peters, MO
Property

Office

9,920 SF
Availability

1 Space

180 SF
For Lease

$500.00/MO
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6036-6038 Weldon Spring Parkway

6036-6038 Weldon Spring Parkway, Weldon Spring, MO
Property

Office

8,562 SF
Availability

2 Spaces

3,710 SF
For Lease

$14.95 - $15.95/SF/YR
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The minimum rental rate for office space in Saint Charles is $13 per square foot. Among listings of office space currently available for lease in Saint Charles, the maximum rental rate is $28 per square foot.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Saint Charles, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 63,000 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in Saint Charles is 2,000 square feet, and the average office space size here is 4,124 square feet.

You can find 51 office listing(s) for lease in Saint Charles, which add up to a total of 260,533 square feet. Availability on the market includes a variety of office use types, such as General Office, Medical Office.

The most common office use type currently available for lease in Saint Charles is General Office, which is offered in 33 or 64.71% of listings. The second-most frequent office use type listed here is Medical Office, which account for 9 or 17.65% of office space currently available.

You can search 2 office sublease listing(s) in Saint Charles, which amount to a total of 36,419 square feet. Sublease opportunities on the market include General Office, Medical Office. The Saint Charles neighborhood or submarket with the most sublease listings available is City Center Park.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In Saint Charles, the greatest concentration of office space for lease opportunities is in City Center Park.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The Saint Charles office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 15.69% of total office space listings in the city are in properties rated Class A. Class B office space accounts for 52.94% of spaces listed on the leasing market. The neighborhood with the most Class B office space is City Center Park. Class C office space makes up 1.96% of office space available in Saint Charles.

Buildings completed in and since the year 2000 account for 24% of office properties in the city and incorporate a total of 699,094 square feet.

Out of the office space listings currently available in Saint Charles, you can find 2 LEED-certified or LEED-proposed option(s). A total of 1 building(s) here earned a LEED-certification — certification level.

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Saint Charles? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Saint Charles, MO Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Saint Charles: 3,234,300 Sq. Ft.

In 2024 the Saint Charles office market encompassed 3,234,300 square feet of space. Out of that total, 518,601 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 939,440 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 44.74% share of Saint Charles office inventory, while Class B office assets represent roughly 39% of the market total.

Saint Charles Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	939,440 Sq. Ft.	29.05%
100k to 500k Sq. Ft.	1,376,272 Sq. Ft.	42.55%
500k to 1M Sq. Ft.	518,601 Sq. Ft.	16.03%

Saint Charles Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	1,447,012 Sq. Ft.	44.74%
Class B	1,261,443 Sq. Ft.	39%
Class C	185,845 Sq. Ft.	5.75%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

51 Office Spaces for Rent in Saint Charles, MO

SSM Health Medical Buildings 1 & 2

Streets of St. Charles - 1450 Beale Street

3817-3841 Millstone Parkway

1000 Technology Drive

Streets of St. Charles - 1520 South 5th Street

Streets of St. Charles

Three Flags Business Center

1600 Heritage Landing

The Commons

2085 Collier Corporate Pkwy

5377 Highway N

2722 South Saint Peters Parkway

119 South Main Street

2300 Highway 94 South Outer Rd

The Streets of St Charles

4071 North Saint Peters Parkway

416 S Main Street

1540 Country Club Plaza Dr

Campus Plaza

3010 North Highway 94

1120 Wolfrum Rd

1 Point West Blvd

6020 Weldon Spring Parkway

Executive Centre I

2046 Queens Brooke Boulevard

6036-6038 Weldon Spring Parkway

Frequently Asked Questions

Saint Charles, MO Office Inventory Breakdown

Total Office Space in Saint Charles: 3,234,300 Sq. Ft.

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51 Office Spaces for Rent in Saint Charles, MO

Frequently Asked Questions

How much does office space cost in Saint Charles, MO?

How much office space do I need?

What types of office space can I lease in Saint Charles, MO?

Can I find sublease office space in Saint Charles, MO?

Where is the best location for office space in Saint Charles, MO?

How long is the average commute to work in Saint Charles, MO?

Where can I find the highest quality office space in Saint Charles, MO?

How do I find the best office space in Saint Charles, MO?

How can I find office space for rent near me?

Saint Charles, MO Office Inventory Breakdown

Total Office Space in Saint Charles: 3,234,300 Sq. Ft.

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About us