Greenville, SC Commercial Real Estate for Lease and Sale

Explore 153 listings of Greenville commercial real estate to find the best space for your business.

1621 East North Street

1621 East North Street, Greenline, Greenville, SC
Property

Office

1,800 SF
Availability

1 Space

1,800 SF
For Lease

$23.00/SF/YR
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±2,150 SF lease opportunity on Augusta Street in Greenville, SC

1429 Augusta St, Augusta Street Area, Greenville, SC
Property

Office
Availability

1 Space

2,150 SF
For Lease Contact for pricing
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One Liberty Square

55 Beattie Place, East Park, Greenville, SC
Property

Office

248,563 SF
Availability

7 Spaces

36,990 SF
Year Built

1983
For Lease

$35.50/SF/YR
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Welborn Street and Oscar Street

Welborn Street and Oscar Street, Southernside Greenville, Greenville, SC
Property

VacantLand
For Sale

$2,500,000
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Office Coworking Retail Industrial

Office Retail Industrial Land
±3,037 SF Sublease Opportunity | Restaurant Ready Building in Greenville, SC

3 Pelham Rd, Overbrook, Greenville, SC
Property

Retail
Availability

1 Space

3,037 SF
Year Built

2015
For Lease Contact for pricing
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105 Lydia St

105 Lydia St, Augusta Street Area, Greenville, SC
Property

Office

2,250 SF
Availability

1 Space

2,250 SF
For Lease

$16.00/SF/YR
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Downtown Greenville Office Space for Lease with Direct Access to ONE City Plaza

103 N. Main Street, Downtown Greenville, Greenville, SC
Property

Office
Availability

1 Space

6,506 SF
For Lease Contact for pricing
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Office Park Patewood - VI

10 Patewood Drive, Overbrook, Greenville, SC
Property

Office

107,274 SF
Availability

3 Spaces

15,113 SF
Year Built

2000
For Lease

$26.50/SF/YR
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301 Augusta Street

301 Augusta Street , Downtown Greenville, Greenville, SC
Property

Office

2,600 SF
Availability

1 Space

250 SF
For Lease Contact for pricing
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Crosspointe Plaza

824 Woods Crossing Rd, Verdae, Greenville, SC
Property

Retail

124,375 SF
Availability

1 Space

11,350 SF
For Lease Contact for pricing
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11 Brendan Way

11 Brendan Way, Overbrook, Greenville, SC
Property

Office

39,504 SF
Availability

1 Space

1,400 SF
Year Built

2001
For Lease

$24.75/SF/YR
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214 Industrial Dr

214 Industrial Dr, Verdae, Greenville, SC
Property

Industrial

90,000 SF
For Sale Contact for pricing
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±2,759-SF Class A Office Space for Sublease in the Historic West End of Downtown Greenville

116 N Markley St, Payne-Logan, Greenville, SC
Property

Office
Availability

1 Space

2,759 SF
For Lease Contact for pricing
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The Greene

1108 S. Main St, Payne-Logan, Greenville, SC
Property

Retail

257,698 SF
Availability

1 Space

1,127 SF
Year Built

2018
For Lease

$25.00/SF/YR
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Poe West

556 Perry Ave, West Greenville, Greenville, SC
Property

Office

10,225 SF
Availability

2 Spaces

5,096 SF
For Lease

$28.00/SF/MO
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Two Liberty Square

75 Beattie Place, East Park, Greenville, SC
Property

Office

185,658 SF
Availability

4 Spaces

7,911 SF
Year Built

1986
For Lease

$35.50/SF/YR
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North Hills Medical Center

800 Pelham Rd, Overbrook, Greenville, SC
Property

Office

46,932 SF
Availability

1 Space

38,307 SF
Year Built

1985
For Lease

$14.00 - $18.00/SF/YR
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St. Francis Women's Center

135 Commonwealth Drive, Overbrook, Greenville, SC
Property

Office

57,600 SF
Availability

1 Space

540 SF
Year Built

1991
For Lease Contact for pricing
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BB&T Tower

301 College Street, Downtown Greenville, Greenville, SC
Property

Office

140,000 SF
Availability

1 Space

130,000 SF
Year Built

1971
For Lease

$26.50/SF/YR
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1305 Laurens Road

1305 Laurens Road, Nicholtown, Greenville, SC
Property

Retail

6,500 SF
Availability

2 Spaces

2,400 SF
For Lease

$12.00/SF/YR
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Poe West

556 Perry Avenue, West Greenville, Greenville, SC
Property

Office

66,597 SF
Availability

3 Spaces

6,576 SF
Year Built

1997
For Lease Contact for pricing
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Downtown Office Buildings

429 N Main St, Heritage, Greenville, SC
Property

Office

16,778 SF
For Sale

$2,750,000
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222 Kerns Ave

222 Kerns Ave, Park Place, Greenville, SC
Property

Industrial

25,200 SF
Availability

1 Space

25,200 SF
For Lease

$9.75/SF/YR
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The Ogletree Building

300 North Main Street, East Park, Greenville, SC
Property

Office

61,047 SF
Availability

3 Spaces

9,951 SF
Year Built

1989
For Lease

$28.50/SF/YR
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300 East McBee Avenue

300 East McBee Avenue, Downtown Greenville, Greenville, SC
Property

Office

165,195 SF
Availability

4 Spaces

82,437 SF
Year Built

1984
For Lease

$34.50/SF/YR
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O'Neal Headquarters

10 Falcon Crest Drive, Overbrook, Greenville, SC
Property

Office

81,400 SF
Availability

1 Space

1,804 SF
Year Built

1994
For Lease

$21.00/SF/YR
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Falls Park on the Reedy - 55 East Camperdown Way

55 East Camperdown Way, Downtown Greenville, Greenville, SC
Property

Office

104,040 SF
Availability

6 Spaces

65,656 SF
Year Built

1992
For Lease

$34.00/SF/YR
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104 South Main Street
Thrive Coworking
104 South Main Street, Greenville, SC
Services

Virtual Office

Open Workspace

Meeting Room

Dedicated Desk
Amenities

Complimentary coffee & tea

Fresh fruit

Happy hour

Lunches

Monthly breakfasts

Parking

Printer

Projector

Snacks

TV/Monitor
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14 Airport Rd

14 Airport Rd, Verdae, Greenville, SC
Property

Office

1,015 SF
Availability

1 Space

1,015 SF
Year Built

1965
For Lease

$17.00/SF/YR
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120 N. Laurens St.

120 N. Laurens St., Downtown Greenville, Greenville, SC
Property

Office

12,840 SF
Availability

1 Space

4,200 SF
For Lease

$21.00/SF/YR
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3309 Laurens Road

3309 Laurens Road, Verdae, Greenville, SC
Property

Industrial

515,728 SF
Availability

1 Space

190,000 SF
Year Built

1968
For Lease Contact for pricing
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Fully Furnished Office Building For Sale or Lease | 5 Legacy Park Rd. Greenville, SC

5 Legacy Park Rd, Verdae, Greenville, SC
Property

Office
Availability

1 Space

3,785 SF
For Lease Contact for pricing
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Spaces Falls Tower
Spaces
355 South Main Street 1st & 2nd Floor, Greenville, SC
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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610 Millennium Park Lane , Unit 7

610 Millennium Park Lane , Unit 7, Verdae, Caldwell, ID
Property

Industrial

7,191 SF
Year Built

2024
For Sale

$1,795,000
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601 E Mcbee Ave

601 E Mcbee Ave, McBee Avenue Area, Greenville, SC
Property

Office

19,033 SF
Availability

3 Spaces

6,724 SF
For Lease

$27.00/SF/YR
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60 E. Antrim Drive

60 E. Antrim Drive, Gower, Greenville, SC
Property

Retail

60,000 SF
Availability

2 Spaces

18,500 SF
For Lease

$15.00 - $25.00/SF/YR
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201 Whitsett Street

201 Whitsett Street, Pettigru Street, Greenville, SC
Property

Office

2,258 SF
For Sale

$725,000
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Fully Furnished Office Building For Sale or Lease | 5 Legacy Park Rd. Greenville, SC

5 Legacy Park Rd, Verdae, Greenville, SC
Property

Office

7,138 SF
For Sale Contact for pricing
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Eastside Medical Center

10 Enterprise Blvd., Overbrook, Greenville, SC
Property

Office

45,200 SF
Availability

4 Spaces

10,403 SF
Year Built

1987
For Lease

$24.00/SF/YR
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St. Francis Medical Plaza

131 Commonwealth Drive, Overbrook, Greenville, SC
Property

Office

62,724 SF
Availability

2 Spaces

3,942 SF
Year Built

2000
For Lease Contact for pricing
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5 Shoppers Drive

5 Shoppers Drive, Nicholtown, Greenville, SC
Property

Retail

1,240 SF
Availability

1 Space

1,240 SF
For Lease

$20.00/SF/YR
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±943-1,010 SF New Mixed-Use Retail Opportunities | Greenville, SC

500 Congaree Rd, Verdae, Greenville, SC
Property

Retail
Availability

1 Space

1,010 SF
Year Built

2023
For Lease Contact for pricing
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Haywood Mall

700 Haywood Rd, Verdae, Greenville, SC
Property

Retail

182,070 SF
Availability

1 Space

182,070 SF
For Lease Contact for pricing
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519 Millennium Park Lane , Unit 2

519 Millennium Park Lane , Unit 2, Verdae, Caldwell, ID
Property

Industrial

14,366 SF
Year Built

2024
For Sale

$3,595,000
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Office Park Patewood - V

80 International Drive, Overbrook, Greenville, SC
Property

Office

103,596 SF
Availability

1 Space

12,083 SF
Year Built

1990
For Lease

$26.50/SF/YR
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400 Augusta Street

400 Augusta Street, Green Avenue, Greenville, SC
Property

Office

45,810 SF
Availability

1 Space

2,105 SF
Year Built

1930
For Lease Contact for pricing
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110 East Court Street

110 East Court Street, Downtown Greenville, Greenville, SC
Property

Office

125,000 SF
Availability

2 Spaces

18,651 SF
Year Built

2017
For Lease

$33.50/SF/YR
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555 Haywood Rd

555 Haywood Rd, Verdae, Greenville, SC
Property

Industrial

26,000 SF
Availability

1 Space

26,000 SF
For Lease

$9.00/SF/YR
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ATM Pad Side Immediately Available | For Lease

201 S Pleasantburg Dr, Gower, Greenville, SC
Property

VacantLand
Availability

1 Space

4,356 SF
For Lease

$30,000.00/YR
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201 Whitsett Street

201 Whitsett Street, Pettigru Street, Greenville, SC
Property

Office

2,258 SF
Availability

1 Space

2,258 SF
For Lease Contact for pricing
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Harbinger - Allendale Building

777 Lowndes Hill Road, Overbrook, Greenville, SC
Property

Office

72,094 SF
Availability

12 Spaces

55,935 SF
Year Built

1984
For Lease

$23.50/SF/YR
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130 South Main Street

130 South Main Street, Downtown Greenville, Greenville, SC
Property

Office

32,500 SF
Availability

2 Spaces

4,287 SF
Year Built

1995
For Lease

$28.00/SF/YR
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Greenville commercial real estate market incorporates 3,119,159 square feet of office space across 74 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Greenville commercial real estate market includes 2,379,021 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Greenville market, there is a total of 943,361 square feet of industrial property.

The listing inventory in Greenville incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Greenville is represented by Office space, which accounts for 974,188 square feet of available listings. Industrial space available in Greenville adds up to 439,725 square feet.

Meanwhile, most of the listings of commercial property for sale in Greenville are in the Office category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Greenville is $25.11 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Greenville can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Greenville, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Greenville is in the Downtown Greenville neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Downtown Greenville area.

Meanwhile, retail space opportunities are most abundant in the Verdae submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Verdae.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $60 per square foot. In particular, the property type commanding the highest lease rates in Greenville was Office space.

Conversely, the highest sale price last year was $11,500,000 that is located at 25 Woods Lake Road.

The average size of a commercial property in Greenville depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Greenville, the average size of an office property is 49,511 square feet.
Retail properties here incorporate an average of 99,126 square feet.
Industrial space in Greenville is in buildings that are, on average 67,383 square feet in size.

Greenville, SC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Greenville currently add up to 1,860,629 square feet. The market offers 63 active office listing(s), which amount to 968,648 square feet and account for 60% of commercial spaces on the market. Local retail availability includes 354,682 square feet across 27 retail space(s). Industrial space for rent opportunities in Greenville amount to 439,725 square feet across a total of 11 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	63	968,648
Retail	27	354,682
Industrial	11	439,725
Other	3	97,574

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Greenville, SC. Currently, there is 437,490 square feet of commercial property for sale here , which includes 10 office building(s) for sale , 2 retail investment opportunity listing(s) , and 7 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	10	219,216
Retail	2	40,828
Industrial	7	171,910
Other	16	5,536

Greenville, SC Commercial Real Estate Market Overview

Strategically located along the Interstate 85 corridor that connects Atlanta with Charlotte, N.C., Greenville, S.C., is one of the fastest-growing urban areas in the state. Commercial real estate in Greenville is home to a diverse range of enterprises and industries, from innovative biotech companies to specialty manufacturing facilities. Greenville County is the centerpiece of the 10-county Upstate region that is considered to be the economic engine of South Carolina and one of the strongest manufacturing centers in the country.

The city began as a small farming community in the late 1700s and transitioned through being a global capital of textile manufacturing and trade to a large and diverse metropolitan area where corporate office, manufacturing, warehousing/distribution operations and many more can thrive together. Greenville is now home to both domestic and international firms of all sizes that benefit from the local pro-business environment and all of the amenities that are necessary for growth.

Greenville, SC Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Greenville, SC?

What factors affect the price of commercial real estate in Greenville, SC?

What is the average rent for commercial space in Greenville, SC?

What are the best areas for commercial real estate in Greenville, SC?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Greenville, SC?

Greenville, SC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Greenville, SC Commercial Real Estate Market Overview

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