Key Largo, FL Commercial Real Estate for Lease and Sale

Explore 8 listing(s) of commercial real estate in Key Largo, FL and 1 nearby to find the best space for your business.

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99451 Overseas Hwy 2nd Floor, Key Largo, FL 33037

99451 Overseas Highway, Port Largo, Key Largo, FL
Space Type

Office
For Lease

$12.00/SF/MO
1 space available / 5,457 SF
View Details
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Damaron Building

99198 Overseas Hwy, Sunset Cove, Key Largo, FL
Space Type

Office
For Lease

$1,973.00/MO
1 space available / 1,000 SF
View Details
Pink Plaza

103400 Overseas Hwy, Cross Key Waterway Estates, Key Largo, FL
Space Type

Office, Retail
For Lease Contact for pricing

2 spaces available / 200 - 16,000 SF
View Details
Tradewinds S.C.

101499 Overseas Hwy, Hibiscus Park, Key Largo, FL
Space Type

Retail
For Lease Contact for pricing

5 spaces available / 1,297 - 3,353 SF
View Details
Pink Plaza

103400 Overseas Highway 1st & 2nd Floor, Key Largo, FL
Space Type

Private Offices
For Lease

Contact for pricing
View Details
Holiday RV

100099 Overseas Highway, Holiday Home-Sites, Key Largo, FL
Space Type

Retail
For Lease

$29,000.00/MO
1 space available / 4,680 SF
View Details
91655 Overseas Hwy

91655 Overseas Hwy, Tavernier Ocean Shores, KEY LARGO, FL
Property Type

Other
For Sale

$2,395,000
Built in 1976 / Property size 4,090 SF
View Details
Tavernier Towne

91200 Overseas Hwy, Camp Pleasant, Tavernier, FL
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,700 SF
View Details
Driftwood Trailer Park

92157 Overseas Hwy, Tavernier Ocean Shores, Key Largo, FL
Property Type

Multi-Family
For Sale

$12,600,000
Built in 1980 / Property size 1,289 SF
View Details
Browse 1 listing(s) within 10 miles of Key Largo, FL
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Alabama Jacks

58000 Card Sound Road, Key Largo, FL
Property Type

Retail
For Sale

$4,900,000
Property size 2,297 SF
View Details

Frequently Asked Questions

The best area for commercial real estate in Key Largo will depend greatly on your needs. The neighborhood with the largest overall number of commercial listings is Hibiscus Park, home to no fewer than 5 listings for space of all types. If you're looking for office space, Sunset Cove has the highest concentration of office listings at 1.
CommercialCafe’s CRE offering in Key Largo is enabled by a network of 6 active brokers from 4 different firms, ensuring a wide variety of listings. Working with an experienced professional can make a real difference. Learn more about the benefits of working with a broker.

To get in touch with a broker, use the "Contact Property" button on this search page or fill in the contact form provided on each individual property’s listing page.
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself, local market conditions, the state of the local economy and the demand for that particular type of commercial property, to name a few.

Key Largo, FL Commercial Space Listings

Commercial Space for Lease - Breakdown

The 6 listings for commercial real estate currently available for rent in Key Largo add up to 37,296 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	2	5,457
Retail	3	27,159
Other	1	4,680

Office properties:

The market has 2 active office listings, encompassing 5,457 square feet.
Key Largo office spaces currently listed on CommercialCafe represent 33% of the total commercial real estate market in Key Largo, compared to an average of 53% across all markets tracked by CommercialCafe.

Retail Space:

There are 3 retail listings available, adding up to a total of 27,159 square feet.
Retail spaces account for approximately 50% of the local commercial market, while the average share taken up by retail in all U.S. markets is 46%.

The data presented in this section was last updated as of October 07, 2026

Key Largo, FL Commercial Real Estate for Lease and Sale

99451 Overseas Hwy 2nd Floor, Key Largo, FL 33037

Damaron Building

Pink Plaza

Tradewinds S.C.

Pink Plaza

Holiday RV

91655 Overseas Hwy

Tavernier Towne

Driftwood Trailer Park

Browse 1 listing(s) within 10 miles of Key Largo, FL

Alabama Jacks

Frequently Asked Questions

Key Largo, FL Commercial Space Listings

Commercial Space for Lease - Breakdown

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