221 N Main St

221 N Main St, Natick, MA 01760

Property Information

  • For Lease Contact for pricing
  • Property Type Office
  • Property Size 28,465 SF
  • Date Updated May 11, 2026

Description

220 North Main Street in Natick offers renovated, flexible office space in a highly visible location on Route 27/9, with direct access to Natick Mall, Route 9, and major regional highways.
The three-story, locally owned and managed building features modern upgrades, on-site showers, ample parking, and walkable amenities—an efficient suburban office option for businesses seeking convenience, access, and a professional setting.

2 Spaces Available

Space Available

Space Type

Office

Lease Rate

Contact for pricing

Total Space

1,200 SF

Divisible Space

1,200 - 3,400 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Space Available

Space Type

Office

Lease Rate

Contact for pricing

Total Space

2,200 SF

Divisible Space

2,200 - 3,400 SF

Available Date

Immediate

Renewal Option

Yes

Sublease

No

Contacts

Craig S. Johnston

R.W. Holmes

Dean Blackey

R.W. Holmes

Location

Located at 221 N Main St, Natick, MA 01760, this property is part of the Natick neighborhood and Worcester Springfield market.

Contact 221 N Main St
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