Downtown San Antonio, San Antonio, TX Commercial Real Estate for Lease and Sale

Explore 62 listing(s) of commercial real estate in Downtown San Antonio, San Antonio, TX to find the best space for your business.

1013 Avenue B

1013 Avenue B, Downtown San Antonio, San Antonio, TX
Space Type

Retail
For Lease Contact for pricing

1 space available / 4,456 SF
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1107 N St Marys St

1107 N St Marys St, Downtown San Antonio, San Antonio, TX
Space Type

Retail
For Lease Contact for pricing

1 space available / 1,500 SF
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401 Villita St

401 Villita St, Downtown San Antonio, San Antonio, TX
Space Type

Retail
For Lease Contact for pricing

1 space available / 44,993 SF
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330 Dwyer Ave

330 Dwyer Ave, Downtown San Antonio, San Antonio, TX
Property Type

VacantLand
For Sale Contact for pricing

Property size 0.92 Acre
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Heimann Building

118 N Medina, Downtown San Antonio, San Antonio, TX
Property Type

Office
For Sale

Subject To Offer
Built in 1923 / Property size 19,329 SF
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315 8th St

315 8th St, Downtown San Antonio, San Antonio, TX
Space Type

Retail
For Lease

$15.00/SF/YR
1 space available / 6,000 SF
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Cubeta Building

322 Martinez St, Downtown San Antonio, San Antonio, TX
Space Type

Office
For Lease

$25.00/SF/YR
1 space available / 4,410 SF
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403-405 East Commerce Street & 306 North Presa Street

405 East Commerce Street, Downtown San Antonio, San Antonio, TX
Space Type

Office
For Lease Contact for pricing

2 spaces available / 1,238 - 5,023 SF
View Details
Geekdom, LC - Geekdom

110 East Houston Street 7th Floor, San Antonio, TX
Space Type

Private Offices
For Lease

Contact for pricing
View Details

Downtown San Antonio, San Antonio, TX Commercial Space Listings

Commercial Space for Lease - Breakdown

The 43 listings for commercial real estate currently available for rent in Downtown San Antonio add up to 1,208,982 square feet across various property types. Here's a breakdown of the available space by category:

Property Type	Count of Listings	Total Sq. Ft.
Office	26	1,030,374
Retail	16	135,048
Other	1	43,560

Office properties:

The market has 26 active office listings, encompassing 1,030,374 square feet.
Downtown San Antonio office spaces currently listed on CommercialCafe represent 60% of the total commercial real estate market in Downtown San Antonio, compared to an average of 53% across all markets tracked by CommercialCafe.

Retail Space:

There are 16 retail listings available, adding up to a total of 135,048 square feet.
Retail spaces account for approximately 37% of the local commercial market, while the average share taken up by retail in all U.S. markets is 46%.

The data presented in this section was last updated as of October 07, 2026

Commercial Space for Sale - Breakdown

There are currently 19 properties listed for sale in the Downtown San Antonio market, adding up to 290,756 square feet of space available for purchase. Here is a breakdown of the commercial space for sale listed locally:

7 office properties
2 retail properties
1 industrial property

The data presented in this section was last updated as of October 07, 2026

Property Type	Count of Listings	Total Sq. Ft.
Office	7	113,487
Retail	2	45,867
Industrial	1	27,044
Other	9	104,358

Downtown San Antonio, San Antonio, TX Commercial Real Estate for Lease and Sale

1013 Avenue B

1107 N St Marys St

401 Villita St

330 Dwyer Ave

Heimann Building

315 8th St

Cubeta Building

403-405 East Commerce Street & 306 North Presa Street

Geekdom, LC - Geekdom

Downtown San Antonio, San Antonio, TX Commercial Space Listings

Commercial Space for Lease - Breakdown

Commercial Space for Sale - Breakdown

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