Portsmouth, NH Commercial Real Estate for Lease and Sale
Explore 70 listing(s) of commercial real estate in Portsmouth, NH to find the best space for your business.
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22 Ladd Street, Unit A, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $33.00/SF/YR
1 space available / 2,072 SF -
100 New Hampshire Avenue, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $16.50/SF/YR
1 space available / 71,370 SF -
405 The Hill, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $795.00/MO
1 space available / 350 SF -
215 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $16.50/SF/YR
1 space available / 12,336 SF -

What type of listing property are you looking for?
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22 Ladd Street, Unit A, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $815,000
Built in 1860 / Property size 2,072 SF -
330 Borthwick Avenue, Meadowbrook, Portsmouth, NHSpace Type- Office
For Lease- $18.00 - $19.50/SF/YR
1 space available / 1,705 SF -
270 West Rd Ste 3, Elwyn Park, Portsmouth, NHSpace Type- Industrial
For Lease- $14.00/SF/YR
1 space available / 4,994 SF -
111 New Hampshire Avenue, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $14.00/SF/YR
1 space available / 56,488 SF -
72 Mirona Rd, Elwyn Park, Portsmouth, NHSpace Type- Retail
For Lease- $16.50 - $17.50/SF/YR
1 space available / 3,331 SF -
170 Commerce Way Suite 200, Portsmouth, NHSpace Type- Private Offices
For Lease-
From $549/month
Space for 1 to 15 people -
990 Lafayette Rd, Elwyn Park, Portsmouth, NHProperty Type- Mixed Use
For Sale- $3,600,000
Built in 1965 / Property size 10,795 SF -
40 Congress St, Haymarket Square, Portsmouth, NHProperty Type- Office
For Sale- $10,000,000
Built in 1878 / Property size 22,601 SF -
2454 Lafayette Road, Hillcrest, Portsmouth, NH -
111 Maplewood Ave, Suite F, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $28.00/SF/YR
2 spaces available / 2,116 - 2,777 SF -
118 Maplewood Avenue, Unit C-1, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $415,000
Built in 1990 / Property size 951 SF -
53 Green St, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $1,195,000
Property size 20,849 SF -
875 Greenland Road, Meadowbrook, Portsmouth, NHSpace Type- Office
For Lease- $12.50 - $15.00/SF/YR
1 space available / 2,500 SF -
500 Maplewood Avenue, Bersum Gardens, Portsmouth, NHSpace Type- Retail
For Lease- $10.71/SF/YR
1 space available / 3,921 SF -
325 Corporate Drive, Sherburne, Portsmouth, NH -
170 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $17.00/SF/YR
2 spaces available / 1,910 - 2,923 SF -
273 Corporate Drive, Sherburne, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
1 space available / 16,027 SF -
230 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
1 space available / 4,930 SF -
Lafayette Rd & White Cedar Boulevard, Colonial Pines, Portsmouth, NHProperty Type- Land
For Sale- $1,999,000
Property size 3.6 Acre -
25 Maplewood Avenue, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $4,500,000
Built in 2020 / Property size 8,712 SF -
210 Commerce Way, Wentworth Acres, Portsmouth, NHSpace Type- Office
For Lease- $19.50/SF/YR
2 spaces available / 1,854 - 3,172 SF -
6 Greenleaf Avenue, Elwyn Park, Portsmouth, NHSpace Type- Office
For Lease- $350.00 - $450.00/MO
2 spaces available / 200 - 250 SF -
11 Portwalk Pl, Portsmouth, NHSpace Type- Private Offices
For Lease-
From $1,500/month
Space for up to 2 people -
110 Chapel Street, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $30.00 - $38.00/SF/YR
1 space available / 4,928 SF -
1 Cate St #1A, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $750,000
Built in 1987 / Property size 2,420 SF -
75 New Hampshire Avenue, Sherburne, Portsmouth, NH -
135 McDonough Street, Portsmouth, NHSpace Type- Private Offices
For Lease-
From $650/month
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100 Market Street, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $35.00/SF/YR
1 space available / 4,870 SF -
500 Maplewood Avenue, Bersum Gardens, Portsmouth, NHSpace Type- Office
For Lease- $10.48/SF/YR
1 space available / 8,202 SF -
4 Cutts Street, Units 3 & 4, Bersum Gardens, Portsmouth, NHSpace Type- Industrial
For Lease- $11.00 - $14.00/SF/YR
3 spaces available / 11,500 - 28,000 SF -
111 New Hampshire Avenue, Sherburne, Portsmouth, NH -
25 Chestnut Street, Haymarket Square, Portsmouth, NHSpace Type- Office
For Lease- $20.00/SF/YR
1 space available / 5,793 SF -
125 Aviation Ave, Sherburne, Portsmouth, NHSpace Type- Industrial
For Lease- $10.00/SF/YR
2 spaces available / 5,320 - 20,500 SF -
375 Banfield Rd, Elwyn Park, Portsmouth, NH -
1 Cate St #1A, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $22.00/SF/YR
1 space available / 2,420 SF -
96 Penhallow Street, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $3,700.00/MO
1 space available / 1,300 SF -
54 Maplewood Avenue #1, North Mill Pond, Portsmouth, NHProperty Type- Office
For Sale- $3,440,000
Built in 2019 / Property size 4,862 SF -
99 Bow St, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $40.00/SF/YR
3 spaces available / 3,296 - 5,552 SF -
299 Hanover St, North Mill Pond, Portsmouth, NHSpace Type- Office
For Lease- $4,500.00/MO
1 space available / 1,821 SF -
1390 Lafayette Road, Elwyn Park, Portsmouth, NH -
110 Corporate Drive, Sherburne, Portsmouth, NH -
Ledgewood Drive, South End Portsmouth, Portsmouth, NHProperty Type- VacantLand
For Sale- Undisclosed; inquire with broker
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755 Banfield Rd, Hillcrest, Portsmouth, NHSpace Type- Office
For Lease- $12.50/SF/YR
1 space available / 2,875 SF -
1950 Lafayette Road, Portsmouth, NH -
300 Heritage Ave, Hillcrest, Portsmouth, NHSpace Type- Industrial
For Lease- $14.25/SF/YR
1 space available / 9,000 SF -
35 Corporate Drive, Sherburne, Portsmouth, NH -
282 Corporate Dr, Sherburne, Portsmouth, NHSpace Type- Office
For Lease- $7.00/SF/YR
1 space available / 3,250 SF -
42 Cutts Street, Bersum Gardens, Portsmouth, NHSpace Type- Other
For Lease Contact for pricing -
22 Market Square, Haymarket Square, Portsmouth, NHSpace Type- Retail, Office
For Lease- $19.00 - $27.10/SF/YR
2 spaces available / 1,550 - 9,600 SF