San Diego, CA Office Spaces for Rent

Find your best San Diego, CA office space among 1,694 for rent listings, which average an asking price of $44.35 per square foot.

Office Market FAQs

9707 Waples Street

9707 Waples St, Sorrento Valley, San Diego, CA
Property

Office
Availability

1 Space

21,375 SF
For Lease Contact for pricing
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FULLY LEASED | 5440 Morehouse Drive | Sorrento Mesa Office

5440 Morehouse Dr, Sorrento Valley, San Diego, CA
Property

Office
Availability

1 Space

1,311 SF
For Lease Contact for pricing
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SOVA Science District

11494 - 11772 Sorrento Valley Rd, Torrey Pines Preserve, San Diego, CA
Property

Office
Availability

1 Space

153,102 SF
For Lease Contact for pricing
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Moda Sorrento

5550 Oberlin Drive, Sorrento Valley, San Diego, CA
Property

Office

22,399 SF
Availability

2 Spaces

22,940 SF
Year Built

1984
For Lease Contact for pricing
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Scripps Ranch Technology Park

10290 Meanley Drive, Scripps Ranch, San Diego, CA
Property

Office

114,000 SF
Availability

1 Space

114,000 SF
For Lease Contact for pricing
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RaDD - 4A - Edge

975 Waterfront Pl., Marina, San Diego, CA
Property

Office

41,776 SF
Availability

2 Spaces

41,776 SF
Year Built

2024
For Lease Contact for pricing
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Seaview Corporate Center

10190 Telesis Ct., Sorrento Valley, San Diego, CA
Property

Office

12,782 SF
Availability

2 Spaces

12,782 SF
Year Built

1986
For Lease Contact for pricing
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800 W Ivy St

800 W Ivy St, Little Italy, San Diego, CA
Property

Office

7,850 SF
Availability

1 Space

1,400 SF
Year Built

2014
For Lease

$3.75/SF/MO
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Headquarters Point- Building B

4910 Headquarters Point, Sorrento Valley, San Diego, CA
Property

Office

123,000 SF
Availability

3 Spaces

32,985 SF
For Lease Contact for pricing
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The Campus at Horton - Bldg. 600

300 Horton Plz., Horton Plaza, San Diego, CA
Property

Office

37,932 SF
Availability

1 Space

37,932 SF
Year Built

2025
For Lease Contact for pricing
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The average rent for office space in San Diego is $44.35 per square foot. The minimum rental rate for office space in San Diego is $1.65 per square foot. Among listings of office space currently available for lease in San Diego, the maximum rental rate is $204 per square foot.

The most common factor that influences cost of office space in any location is the property class rating. For example, San Diego office space rated Class A asks an average of $52.46 per square foot. Class B office space in San Diego costs $35.05 per square foot, on average. Listings of office space in Class C buildings asked an average of $36.33 per square foot.

For more details on San Diego office space rent and sales prices, as well as overall market quality and new construction data, see San Diego Office Market Trends.
Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in San Diego, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 212,851 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in San Diego is 3,778 square feet, and the average office space size here is 9,621 square feet.
You can find 1,694 office listing(s) for lease in San Diego, which add up to a total of 16,523,404 square feet. Availability on the market includes a variety of office use types, such as General Office, Medical Office, Flex - Office, Creative Office, R&D - Office.

The most common office use type currently available for lease in San Diego is General Office, which is offered in 1,142 or 67.41% of listings. The second-most frequent office use type listed here is Medical Office, which account for 145 or 8.56% of office space currently available. On the other end of the spectrum, the office use type least common among local listings is Showroom - Office, which is available in 2 listing(s).
You can search 103 office sublease listing(s) in San Diego, which amount to a total of 2,084,900 square feet. Sublease opportunities on the market include General Office, Flex - Office, R&D - Office. The San Diego neighborhood or submarket with the most sublease listings available is University City.
The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In San Diego, the greatest concentration of office space for lease opportunities is in Core - Columbia, Mission Valley East, Sorrento Valley.
Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.
The San Diego office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 44.16% of total office space listings in the city are in properties rated Class A. You will find the highest concentration of Class A office space in the Core - Columbia neighborhood of San Diego. Class B office space accounts for 46.58% of spaces listed on the leasing market. The neighborhood with the most Class B office space is Sorrento Valley. Class C office space makes up 2.6% of office space available in San Diego.

Buildings completed in and since the year 2000 account for 24.15% of office properties in the city and incorporate a total of 15,168,899 square feet. About 3.59% of office space in San Diego is in buildings that have been renovated at least once since 2000.

Out of the office space listings currently available in San Diego, you can find 300 LEED-certified or LEED-proposed option(s). A total of 50 building(s) here earned a LEED-certification — certification levelPlatinum (3), Gold (29), Silver (16). The local market includes 4 LEED-proposed office building(s) awaiting certification in San Diego.
There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.
Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of San Diego? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

San Diego, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in San Diego: 93,412,194 Sq. Ft.

In 2025 the San Diego office market encompassed 93,412,194 square feet of space. Out of that total, 4,770,611 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 23,187,282 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 50.63% share of San Diego office inventory, while Class B office assets represent roughly 44.77% of the market total.

San Diego Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	23,187,282 Sq. Ft.	24.82%
100k to 500k Sq. Ft.	55,826,835 Sq. Ft.	59.76%
500k to 1M Sq. Ft.	4,770,611 Sq. Ft.	5.11%

San Diego Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A+	2,657,663 Sq. Ft.	2.85%
Class A	47,295,637 Sq. Ft.	50.63%
Class B	41,821,946 Sq. Ft.	44.77%
Class C	1,636,948 Sq. Ft.	1.75%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

San Diego, CA Office Market Overview

San Diego, Calif., is the eighth-largest city in the U.S. and the second-largest in California, as well as part of the San Diego-Tijuana conurbation, which straddles the Mexican border. The city is famous for its sunny beaches, rich culture, vast U.S. Navy presence and talented workforce.

The main economic sectors in San Diego include military and defense, innovation, tourism, education and healthcare. Universities here — such as the University of California San Diego and San Diego State University — rank among the best in the nation for international business, and thousands of students here graduate with STEM degrees each year. San Diego is also one of the best cities in the country for Millennials to live and work.

With more and more businesses launching with the help of accelerators and incubators, demand for prime office in San Diego is strong. Nearly half of all San Diego office inventory is Class A.

San Diego, CA in the news

Top 25 U.S. Metros for Life Sciences: Boston, San Francisco & New York Lead the Way

San Diego was the fourth-best metro for life sciences in the U.S., boasting notable scores for life sciences in the local office market, total life sciences square footage added since 2018, for innovation, and more.

Portfolio Deals Take the Podium for the Most Expensive Office Sales of 2023

The sale of Cubic Mission and Corporation HQs portfolio, totaling 350,000 square feet of San Diego office space and claiming more than $175 million, ranked among the 20 largest office deals of 2023.

Office Pipeline 2024: Boston Leads by Construction Volume, Strong Seattle Presence Among Top 20 Projects Under Construction

San Diego was the 2nd California market in the top 10 and placed fourth in our ranking, with more than 5 million square feet of office space projects under construction at the start of 2024.

Artificial Intelligence in the U.S.: Top Innovators & Hottest Markets

San Diego was the last of the four California entries to rank among the 25 most innovative metros in the U.S., in no small part due to semiconductor and wireless communications technology manufacturer Qualcomm Technologies, Inc., which is headquartered here.

2022’s Top 50 Most Expensive Office Sales

Further south, a portfolio sale of San Diego office spaces was just shy of the top 10 most expensive office transactions of 2022.

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San Diego, CA Office Spaces for Rent

9707 Waples Street

FULLY LEASED | 5440 Morehouse Drive | Sorrento Mesa Office

SOVA Science District

Moda Sorrento

Scripps Ranch Technology Park

RaDD - 4A - Edge

Seaview Corporate Center

800 W Ivy St

Headquarters Point- Building B

The Campus at Horton - Bldg. 600

Frequently Asked Questions

San Diego, CA Office Inventory Breakdown

Total Office Space in San Diego: 93,412,194 Sq. Ft.

San Diego, CA Office Market Overview

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