San Diego, CA Commercial Real Estate for Lease and Sale
Explore 1,133 listing(s) of commercial real estate in San Diego, CA to find the best space for your business.
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6042 Cornerstone Court West, Sorrento Valley, San Diego, CASpace Type- Office
For Lease- $1.75/SF/MO
3 spaces available / 3,157 - 8,388 SF -
5505 Morehouse Drive, Sorrento Valley, San Diego, CA -
4655 Executive Drive, University City, San Diego, CASpace Type- Office
For Lease- $6.10 - $6.30/SF/MO
4 spaces available / 2,573 - 22,853 SF -
9635 Granite Ridge Drive, Serra Mesa, San Diego, CA -

What type of listing property are you looking for?
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845 15th Street 1st-4th Floor, San Diego, CASpace Type- Private Offices
For Lease-
From $519/month
Space for 1 to 15 people -
2651 Via De La Valle, North City, Del Mar, CA -
701 B St., Core - Columbia, San Diego, CA -
15333 Avenue of Science, Carmel Mountain, San Diego, CA -
Piper Ranch Rd., Otay Mesa, San Diego, CA -
6114 Nancy Ridge Drive, Sorrento Valley, San Diego, CASpace Type- Industrial
For Lease- $1.09/SF/MO
1 space available / 75,000 SF -
4115 Sorrento Valley Blvd, Sorrento Valley, San Diego, CASpace Type- Office
For Lease- $3.00/SF/MO
1 space available / 6,000 SF -
800 Pacific Coast Hwy., Marina, San Diego, CA -
12730 High Bluff Drive, Carmel Valley, San Diego, CA -
2323 Avenida Costa Este, Otay Mesa, San Diego, CA -
9885 Mesa Rim Road, Sorrento Valley, San Diego, CASpace Type- Industrial
For Lease- $2.25/SF/MO
1 space available / 2,041 SF -
12812 Rancho Penasquitos Blvd, Rancho Penasquitos, San Diego, CASpace Type- Retail
For Lease- $27.60/SF/YR
1 space available / 1,164 SF -
10180 Telesis Ct., Sorrento Valley, San Diego, CA -
1230 Columbia Street, Core - Columbia, San Diego, CA -
9325 Sky Park Court, Kearny Mesa, San Diego, CA -
9233 Balboa Ave., Kearny Mesa, San Diego, CA -
10355 Science Center Drive, University City, San Diego, CA -
5451 Oberlin Drive, Sorrento Valley, San Diego, CA -
7999 Vickers Street, Kearny Mesa, San Diego, CASpace Type- Office
For Lease- $1.55/SF/MO
1 space available / 10,253 SF -
17095 Via Del Campo, Rancho Bernardo, San Diego, CA -
10511-10543 4S Commons Dr, 4S Ranch, San Diego, CA -
8451 Miralani Dr., Miramar, San Diego, CA -
1210 Air Wing Road, Otay Mesa, San Diego, CA -
6501 Mission Gorge Road, Grantville, San Diego, CA -
10643 Westview Pkwy, Mira Mesa, San Diego, CA -
4215 Sorrento Valley Blvd, Sorrento Valley, San Diego, CA -
8989 Rio San Diego Drive, Mission Valley East, San Diego, CASpace Type- Office
For Lease- $3.05/SF/MO
1 space available / 2,250 SF -
310 Euclid Avenue, Lincoln Park, San Diego, CASpace Type- Retail
For Lease- $2.75/SF/MO
1 space available / 1,488 SF -
6180 Business Center Ct, Ocean View Hills, San Diego, CAProperty Type- Industrial
For Sale- $20,856,150
Property size 92,694 SF -
12235 El Camino Real, Carmel Valley, San Diego, CA -
15015 Avenue of Science, Carmel Mountain, San Diego, CASpace Type- Office
For Lease- $2.60/SF/MO
2 spaces available / 9,483 - 9,590 SF -
1050 Kettner Blvd, Ste. D, San Diego, CASpace Type- Private Offices
For Lease-
From $400/month
Space for up to 4 people -
960 Sherman Street, Morena, San Diego, CA -
825 N. Harbor Dr., Marina, San Diego, CA -
1450 Frazee Road, Mission Valley East, San Diego, CA -
1855 Dornoch Court, Otay Mesa, San Diego, CASpace Type- Industrial
For Lease- $1.15/SF/MO
1 space available / 25,000 SF -
4901 Morena Blvd., Bay Ho, San Diego, CASpace Type- Office
For Lease- $26.40 - $27.12/SF/YR
2 spaces available / 886 - 1,115 SF -
3111 Camino Del Rio North, Mission Valley East, San Diego, CASpace Type- Office
For Lease- $3.65 - $4.30/SF/MO
4 spaces available / 1,330 - 6,799 SF -
2550 5th Ave., Bankers Hill - Park West, San Diego, CA -
1455 Frazee Road, Mission Valley East, San Diego, CASpace Type- Office
For Lease- $26.40/SF/YR
6 spaces available / 2,340 - 8,438 SF -
9265 Activity Rd., Miramar, San Diego, CASpace Type- Industrial
For Lease- $20.40 - $21.00/SF/YR
2 spaces available / 1,706 - 3,166 SF -
12264 El Camino Real, Carmel Valley, San Diego, CA -
9920 Pacific Heights Suites 150, San Diego, CASpace Type- Private Offices
For Lease-
From $556/month
Space for 1 to 15 people -
9909 Mira Mesa Blvd, Scripps Ranch, San Diego, CA -
4755 Nexus Center Dr., University City, San Diego, CA -
13500 Evening Creek Drive North, Sabre Springs, San Diego, CA -
2820-30 Lytton Street, Loma Portal, San Diego, CAProperty Type- Other
For Sale- $2,250,000
Built in 1924 / Property size 2,996 SF -
849 West Harbor Drive, Marina, San Diego, CA -
2650 Camino Del Rio North 1st Floor, San Diego, CASpace Type- Private Offices
For Lease-
From $849/month
Space for 1 to 15 people