San Diego, CA Commercial Real Estate for Lease and Sale
Explore 1,135 listing(s) of commercial real estate in San Diego, CA to find the best space for your business.
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5330 Napa St., Morena, San Diego, CASpace Type- Office
For Lease- $29.52/SF/YR
1 space available / 3,382 SF -
2869 Historic Decatur Road, San Diego, CASpace Type- Private Offices
For Lease-
From $1,500/month
Space for 1 to 13 people -
16625 Dove Canyon Road, 4S Ranch, San Diego, CA -
11230 Sorrento Valley Rd, Torrey Pines Preserve, San Diego, CA -

What type of listing property are you looking for?
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7520 Airway Rd, Otay Mesa, San Diego, CA -
5910 Pacific Center Blvd., Sorrento Valley, San Diego, CASpace Type- Office
For Lease- $83.40/SF/YR
1 space available / 420,000 SF -
5550 Oberlin Drive, Sorrento Valley, San Diego, CA -
1045 14th Street, East Village, San Diego, CASpace Type- Office
For Lease- $2.45/SF/MO
1 space available / 8,714 SF -
1747 Pacific Highway, Harborview, San Diego, CA -
6650 Nancy Ridge Dr, Sorrento Valley, San Diego, CA -
4902 Headquarters Pt, Sorrento Valley, San Diego, CA -
11211-11225 Camino Ruiz, Mira Mesa, San Diego, CA -
10290 Meanley Drive, Scripps Ranch, San Diego, CA -
2185 Station Village Way, Mission Valley East, San Diego, CA -
8425 Otay Mesa Road, Otay Mesa, San Diego, CA -
3964 30th St, North Park, San Diego, CA -
7622 Paseo De La Fuente, Otay Mesa, San Diego, CA -
9685 Via Excelencia, Miramar, San Diego, CA -
SWC Friars Road & Escondido Fwy, Mission Valley East, San Diego, CA -
1750 Kettner Boulevard #111, San Diego, CA -
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10511 4S Commons Drive, 4S Ranch, San Diego, CA -
10981 San Diego Mission Rd, Grantville, San Diego, CASpace Type- Office
For Lease- $1.85/SF/MO
2 spaces available / 1,752 - 2,768 SF -
9323-9393 Activity Rd., Miramar, San Diego, CASpace Type- Industrial
For Lease- $18.60 - $19.80/SF/YR
4 spaces available / 1,500 - 1,800 SF -
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2031 Commercial Street, San Diego, CA -
140 W Broadway, Core - Columbia, San Diego, CA -
5703 Oberlin Drive #106, San Diego, CA -
7094 Miramar Road, Miramar, San Diego, CA -
NEQ Mission Center Rd & Camino de la Reina Mission Valley, Serra Mesa, San Diego, CA -
7222 Airway Road, Otay Mesa, San Diego, CA -
12812 Rancho Penasquitos Blvd, Suite O, Rancho Penasquitos, San Diego, CASpace Type- Retail
For Lease- $2.30/SF/MO
1 space available / 1,100 SF -
6262 Ferris Sq., Sorrento Valley, San Diego, CAProperty Type- Industrial
For Sale- $2,760,800
Built in 1987 / Property size 6,904 SF -
10428 Paragon Rd., Otay Mesa, San Diego, CA -
8646 Commerce Avenue, Miramar, San Diego, CAProperty Type- Industrial
For Sale- $2,135,000
Built in 1977 / Property size 4,610 SF -
8369 Vickers Street, Kearny Mesa, San Diego, CASpace Type- Office
For Lease- $1.85 - $2.00/SF/MO
5 spaces available / 610 - 1,850 SF -
5025-31 Brighton Avenue, Ocean Beach, San Diego, CAProperty Type- Multi-Family
For Sale- $2,159,000
Built in 1948 / Property size 2,332 SF -
6910 Miramar Rd, Miramar, San Diego, CASpace Type- Retail
For Lease- $2.00/SF/YR
1 space available / 3,942 SF -
10429 Paragon Rd., Otay Mesa, San Diego, CA -
6530 Gateway Park Drive, Otay Mesa, San Diego, CASpace Type- Industrial
For Lease- $0.86/SF/MO
1 space available / 23,011 SF -
10055 Marconi Dr, Otay Mesa, San Diego, CASpace Type- Industrial
For Lease- $1.45/SF/YR
1 space available / 1,371 SF -
835 5th Ave, Gaslamp, San Diego, CASpace Type- Office
For Lease- $1.75 - $3.50/SF/MO
11 spaces available / 268 - 4,421 SF -
9930 Mira Mesa Blvd, Miramar Ranch, San Diego, CA -
12651 & 12671 High Bluff Dr, Carmel Valley, San Diego, CA -
2535 Midway Dr., Midway, San Diego, CA -
2926 University Avenue, North Park, San Diego, CA -
3344 Fourth Avenue #200, San Diego, CASpace Type- Private Offices
For Lease-
From $620/month
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6134 Nancy Ridge Dr., Sorrento Valley, San Diego, CA -
7920-7950 Miramar Road, Miramar, San Diego, CA -
10451 Paragon Rd., Otay Mesa, San Diego, CA -
El Cajon Blvd & 33rd St, Talmadge, San Diego, CA -
11045 Roselle St., Torrey Pines Preserve, San Diego, CA -
6310 - 6370 Nancy Ridge Dr, Sorrento Valley, San Diego, CA