South San Francisco, CA Commercial Real Estate for Lease and Sale
Explore 115 listings of South San Francisco commercial real estate to find the best space for your business.
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6000 Shoreline Court, Paradise Valley, South San Francisco, CAProperty- Office
- 139,372 SF
Availability- 2 Spaces
- 20,245 SF
Year Built- 2001
For Lease Contact for pricing -
225 Gateway Blvd, Gateway, South San Francisco, CAProperty- Office
- 106,076 SF
Availability- 5 Spaces
- 113,979 SF
Year Built- 1998
For Lease Contact for pricing -
245 South Spruce Avenue, Lindenville, South San Francisco, CAProperty- Industrial
- 559,605 SF
Availability- 5 Spaces
- 10,250 SF
Year Built- 1957
For Lease- $26.28 - $37.32/SF/YR
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499 Forbes Blvd, The East Side, South San Francisco, CAProperty- Flex Space
- 144,209 SF
Availability Contact for availabilityYear Built- 2022
For Lease Contact for pricing -
What type of listing property are you looking for?
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390 Swift Ave, The East Side, S San Francisco, CA -
611 Gateway Blvd, Gateway, S San Francisco, CAProperty- Office
- 260,337 SF
Availability- 1 Space
- 24,768 SF
Year Built- 2002
For Lease Contact for pricing -
100 Produce Avenue, Lindenville, South San Francisco, CAProperty- Office
- 41,448 SF
Availability- 2 Spaces
- 3,917 SF
Year Built- 1986
For Lease- $0.80 - $1.50/SF/MO
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233 E Harris Ave, The East Side, South San Francisco, CAProperty- Industrial
Availability- 1 Space
- 60,000 SF
Year Built- 1979
For Lease- $1.55/SF/MO
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1 Corporate Drive, South San Francisco, CA1 Corporate Drive
Bonneville LabsServices- Meeting Room
- Private Office
Amenities -
201 Haskins Way, South San Francisco, CA201 Haskins Way
Lilly Gateway LabsServices- Meeting Room
- Private Office
Amenities -
750 Gateway Boulevard, South San Francisco, CA750 Gateway Boulevard
Bonneville LabsServices- Meeting Room
- Private Office
Amenities -
349 Oyster Point Blvd, Oyster Point, South San Francisco, CA -
216-218 Linden Ave, Downtown South San Francisco, South San Francisco, CAProperty
- Retail
- 19,800 SF
Availability- 3 Spaces
- 1,672 SF
Year Built- 1912
For Lease Contact for pricing -
580 Dubuque Avenue/SPUR Phase I (IQHQ), Gateway, S San Francisco, CAProperty
- Unassigned
- 330,350 SF
Availability- 7 Spaces
- 330,350 SF
Year Built- 2025
For Lease- $84.00/SF/YR
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312 Harbor Way, The East Side, South San Francisco, CA
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348 Grand Ave, Downtown South San Francisco, South San Francisco, CAProperty
- Retail
Availability- 1 Space
- 3,000 SF
For Lease- $2.88/SF/MO
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301 Grand Ave, Downtown South San Francisco, South San Francisco, CAProperty
- Office
Availability- 1 Space
- 3,689 SF
Year Built- 1973
For Lease- $1.66/SF/MO
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212-218 Ryan Way, Lindenville, South San Francisco, CA
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485 Eccles Avenue, The East Side, South San Francisco, CAProperty
- Office
- 160,000 SF
Availability- 4 Spaces
- 144,700 SF
Year Built- 2024
For Lease- $7.25/SF/MO
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406 Cabot Road, The East Side, South San Francisco, CAProperty
- VacantLand
- 17,000 SF
Availability- 1 Space
- 12,000 SF
Year Built- 1965
For Lease- $1.00/SF/MO
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340 Shaw Rd, Lindenville, S San Francisco, CA
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410 Grand Ave, E., The East Side, S San Francisco, CAProperty
- Industrial
- 22,270 SF
Availability- 1 Space
- 22,270 SF
Year Built- 1980
For Lease Contact for pricing -
121 Maple Ave, S., Lindenville, S San Francisco, CAProperty
- Industrial
- 38,750 SF
Year Built- 1978
For Sale- $1,250,000
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128 Brentwood Dr, Brentwood Park, South San Francisco, CAProperty
- Retail
- 18,767 SF
Availability- 2 Spaces
- 2,778 SF
Year Built- 1952
For Lease Contact for pricing -
6 S. Linden Avenue, Lindenville, South San Francisco, CA
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101 TERMINAL CT, Lindenville, South San Francisco, CAProperty
- VacantLand
- 378,068 SF
Availability- 1 Space
- 378,068 SF
For Lease- $0.60/SF/MO
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458 Carlton Ct, The East Side, South San Francisco, CAProperty
- Industrial
- 4,876 SF
Availability- 1 Space
- 2,627 SF
For Lease- $5.00/SF/MO
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220 S Spruce Ave, Orange Park, South San Francisco, CAProperty
- Office
Availability- 1 Space
- 1,550 SF
Year Built- 1984
For Lease- $2.25/SF/MO
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212-218 Ryan Way, Lindenville, South San Francisco, CA
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105 Associated Rd, Gateway, S San Francisco, CAProperty
- Industrial
- 29,897 SF
Availability- 1 Space
- 29,897 SF
Year Built- 1954
For Lease Contact for pricing -
6 S Linden Ave, Lindenville, South San Francisco, CA
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701 Gateway Blvd , Gateway, South San Francisco, CAProperty
- Office
Availability- 1 Space
- 29,470 SF
Year Built- 1998
For Lease- $2.00/SF/MO
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161 Starlite Street, Lindenville, South San Francisco, CAProperty
- Industrial
- 60,622 SF
Availability- 1 Space
- 27,990 SF
Year Built- 1961
For Lease- $1.75/SF/MO
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1341 San Mateo Ave, Lindenville, South San Francisco, CA
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681 Gateway Boulevard, South San Francisco, CA
681 Gateway Boulevard
Lilly Gateway LabsServices- Meeting Room
- Private Office
Amenities -
201 Cypress Ave, Downtown South San Francisco, South San Francisco, CAProperty
- Industrial
- 10,067 SF
For Sale- $2,900,000
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132 Southwood Center, Southwood, South San Francisco, CAProperty
- Multi-Family
- 5,440 SF
Year Built- 1958
For Sale- $2,300,000
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175 Sylvester Rd, Gateway, S San Francisco, CAProperty
- Industrial
- 74,562 SF
Availability- 1 Space
- 74,562 SF
Year Built- 1957
For Lease Contact for pricing -
212-218 Ryan Way, Lindenville, South San Francisco, CA
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100 Grand Ave, E., Downtown South San Francisco, S San Francisco, CAProperty
- Industrial
- 70,728 SF
Availability- 1 Space
- 20,728 SF
Year Built- 1954
For Lease Contact for pricing -
384 Oyster Point Blvd, Oyster Point, South San Francisco, CAProperty
- Industrial
- 57,444 SF
Availability- 4 Spaces
- 21,538 SF
Year Built- 1985
For Lease- $1.75/SF/MO
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373 Oyster Point Blvd, Oyster Point, San Francisco, CAProperty
- Office
- 865,000 SF
Availability- 3 Spaces
- 865,000 SF
Year Built- 2025
For Lease Contact for pricing -
570 Eccles Ave, The East Side, South San Francisco, CA -
486 Cabot Rd, The East Side, S San Francisco, CAProperty
- Unassigned
- 16,000 SF
Availability- 1 Space
- 6,275 SF
Year Built- 1967
For Lease Contact for pricing -
988 El Camino Real, Orange Park, South San Francisco, CAProperty
- Retail
- 10,000 SF
Availability- 3 Spaces
- 2,231 SF
Year Built- 2022
For Lease Contact for pricing -
233 East Harris Avenue, The East Side, South San Francisco, CAProperty
- Industrial
- 60,225 SF
Availability- 1 Space
- 5,000 SF
Year Built- 1975
For Lease Contact for pricing -
200 E Grand Ave, The East Side, South San Francisco, CA
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264 S Maple Ave, Lindenville, South San Francisco, CA
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407 Cabot Rd, The East Side, South San Francisco, CAProperty
- Industrial
- 17,000 SF
Availability- 2 Spaces
- 1,649 SF
Year Built- 1965
For Lease- $5.00/SF/MO
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900 Gateway Blvd, The East Side, San Francisco, CA
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350 Harbor Wy, The East Side, S San Francisco, CA
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475 Eccles Avenue, The East Side, South San Francisco, CAProperty
- Office
- 160,000 SF
Availability- 4 Spaces
- 129,600 SF
Year Built- 2024
For Lease- $7.25/SF/MO